The pathophysiology of acute mountain sickness and high-altitude cerebral edema, the
cerebral forms of high-altitude illness, remain uncertain and controversial. Persistently …

Abstract Willmann, Gabriel, Florian Gekeler, Kai Schommer, and Peter Bärtsch. Update on
high altitude cerebral edema including recent work on eye. High Alt Med Biol. 15: 112–122 …

Symptoms of acute mountain sickness (AMS) may appear above 2,500 m altitude, if the time
allowed for acclimatization is insufficient. As the mechanisms underlying brain adaptation to …

Background: Obstructive sleep apnea (OSA) is accompanied by both gray and white matter
differences in brain areas that regulate autonomic, cognitive, and mood functions, which are …

Objective The study was undertaken to determine whether normobaric hypoxia causes
elevated brain volume and intracranial pressure in individuals with symptoms consistent …

We sought to understand the mechanisms underlying cognitive deficits that are reported to
affect non-native subjects following their prolonged stay and/or work at high altitude (HA) …

Hypercapnia challenge (eg inhalation of CO2) has been used in calibrated fMRI as well as
in the mapping of vascular reactivity in cerebrovascular diseases. An important assumption …

Following prolonged exposure to hypoxic conditions, for example, due to ascent to high
altitude, stroke, or traumatic brain injury, cerebral edema can develop. The exact nature and …

Background Structural and functional networks can be reorganized to adjust to
environmental pressures and physiologic changes in the adult brain, but such processes …

Introduction We hypothesized that cerebral alterations in edema, perfusion, and/or
intracranial pressure (ICP) are related to the development of acute mountain sickness …