Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …

DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Motivation: DNA methylation is an epigenetic modification with important roles in many
biological processes and diseases. Bisulfite sequencing (BS-seq) has emerged recently as …

We have developed a new generation of genome-wide DNA methylation BeadChip which
allows high-throughput methylation profiling of the human genome. The new high density …

DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …

Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

Tissue specific patterns of methylated cytosine residues vary with age, can be altered by
environmental factors, and are often abnormal in human disease yet the cellular …

DNA methylation is the most stable type of epigenetic modification modulating the
transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report …

Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …