Pancreatic Ductal Adenocarcinoma (PDAC): A Review of Recent Advancements Enabled by Artificial Intelligence

A Mukund, MA Afridi, A Karolak, MA Park, JB Permuth… - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic Ductal Adenocarcinoma (PDAC) remains one of the deadliest
forms of cancer, characterized by high rates of metastasis, late detection, and poor …

Coordinated single-cell tumor microenvironment dynamics reinforce pancreatic cancer subtype

K Oh, YJ Yoo, LA Torre-Healy, M Rao, D Fassler… - Nature …, 2023 - nature.com
Bulk analyses of pancreatic ductal adenocarcinoma (PDAC) samples are complicated by the
tumor microenvironment (TME), ie signals from fibroblasts, endocrine, exocrine, and immune …

[HTML][HTML] Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy

NK Horvat, I Karpovsky, M Phillips… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor. Prognosis
is poor and survival is low in patients diagnosed with this disease, with a survival rate of …

The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids

S Bose, X Shen - Cell Stem Cell, 2024 - cell.com
The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids:
Cell Stem Cell Skip to Main Content Advertisement Cell Stem Cell This journal offers authors …

Updates in Molecular Profiling of Pancreatic Ductal Adenocarcinoma

JJ Lee, JJ Yeh - Surgical Clinics, 2024 - surgical.theclinics.com
Despite significant research efforts and clinical trials, pancreatic ductal adenocarcinoma
(PDAC) remains a deadly disease and is now projected to become the second leading …

Integration of Molecular, Histological, and Immunological Markers of Clinical Performance in Pancreatic Ductal Adenocarcinoma and Breast Cancer

L Torre-Healy - 2023 - search.proquest.com
Molecular subtyping in tumors has been a staple of oncology research for decades.
However, we spend more time redefining subtypes than we do generating workflows for …