Indoor air pollution with toxic volatile organic compounds (VOCs) and fine particulate matter
(PM2. 5) is a threat to human health, causing cancer, leukemia, fetal malformation, and …

A low vitamin D status is associated with an increased risk of various cancers, such as of
colon, breast, prostate and hematological cells. The biologically most active vitamin D …

Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …

Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

Chromatin regulation is essential to regulate genes and genome activities. In plants, the
alteration of histone modification and DNA methylation are coordinated with changes in the …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Uncontrolled overgrowth of cells, such as in cancer, is an unavoidable risk in life that affects
nearly every second individual in industrialized countries. However, in part this risk can be …

Osteosarcoma (OS) is a bone tumor of mesenchymal origin, most frequently occurring
during the rapid growth phase of long bones, and usually located in the epiphyseal growth …