Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

The concept that individuals with the same disease and a similar clinical presentation may
have very different outcomes and need very different therapies is not novel. With the …

To avoid conflicting and deleterious outcomes, eukaryotic cells often confine second
messengers to spatially restricted subcompartments. The smallest signaling unit is the Ca2+ …

Renal transplantation is now the best treatment for end-stage renal failure. To avoid
rejection and prolong graft function, organ recipients need immunosuppressive therapy. The …

Analysis of the transcriptional profile of graft biopsies represents a promising strategy to
study T cell–mediated-rejection (TCMR), also known as acute cellular rejection. However …

Background Inflammation, an important event of cellular defensive system, can be triggered
by a variety of factors such as pathogens, allergens, damaged cells and toxic compounds …

Adoptive T cell therapy (ACT) is a safe and effective personalized cancer immunotherapy
that can comprise naturally occurring ex vivo expanded cells (eg, tumor-infiltrating …

The intervention of inflammation disorders with conventional synthetic drugs has several
hazards. Medicinal plants and their byproducts are beneficial in the treatment of …

Varicella-zoster virus causes both varicella (chickenpox) and herpes zoster (shingles).
Although varicella incidence has dramatically declined since introduction of the live …

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare disease associated with
vascular inflammation and multisystem organ damage. The literature reporting EGPA …