Influence of opioids on immune function in patients with cancer pain: from bench to bedside

JW Boland, AG Pockley - British journal of pharmacology, 2018 - Wiley Online Library
In patients with cancer, opioids are principally used for the management of acute surgical
and chronic cancer‐related pain. However, opioids have many non‐analgesic effects …

The polypharmacological effects of cannabidiol

J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

Involvement of Opioid System and TRPM8/TRPA1 Channels in the Antinociceptive Effect of Spirulina platensis

MA Freitas, A Vasconcelos, ECD Gonçalves… - Biomolecules, 2021 - mdpi.com
Spirulina platensis is a “super-food” and has attracted researchers' attention due to its anti-
inflammatory, antioxidant, and analgesic properties. Herein, we investigated the …

Risk of developing comorbidities among women with endometriosis: a retrospective matched cohort study

ES Surrey, AM Soliman, SJ Johnson… - Journal of women's …, 2018 - liebertpub.com
Background: Endometriosis has been associated with higher rates of various chronic
conditions, but its epidemiological data are fragmented and dated. We sought to compare …

[HTML][HTML] Interaction of neurotransmitters and neurochemicals with lymphocytes

D Kerage, EK Sloan, SR Mattarollo… - Journal of …, 2019 - Elsevier
Neurotransmitters and neurochemicals can act on lymphocytes by binding to receptors
expressed by lymphocytes. This review describes lymphocyte expression of receptors for a …

[HTML][HTML] COVID-19 and substance use disorders: Recommendations to a comprehensive healthcare response. an international society of addiction medicine practice …

A Farhoudian, A Baldacchino, N Clark… - Basic and Clinical …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus Disease 2019 (COVID-19) is escalating all over the world and has
higher morbidities and mortalities in certain vulnerable populations. People Who Use Drugs …

The interplay between chronic pain, opioids, and the immune system

V Malafoglia, S Ilari, L Vitiello, M Tenti… - The …, 2022 - journals.sagepub.com
Chronic pain represents one of the most serious worldwide medical problems, in terms of
both social and economic costs, often causing severe and intractable physical and …

Immunomodulatory protein hydrolysates and their application

MBG Kiewiet, MM Faas, P De Vos - Nutrients, 2018 - mdpi.com
Immunomodulatory protein hydrolysate consumption may delay or prevent western immune-
related diseases. In order to purposively develop protein hydrolysates with an optimal and …

Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank

KJA Johnston, J Ward, PR Ray, MJ Adams… - PLoS …, 2021 - journals.plos.org
Chronic pain is highly prevalent worldwide and imparts a significant socioeconomic and
public health burden. Factors influencing susceptibility to, and mechanisms of, chronic pain …

Immunomodulatory role of neuropeptides in the cornea

S Puri, BM Kenyon, P Hamrah - Biomedicines, 2022 - mdpi.com
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …