Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …

Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …

Accumulation of tau and amyloid-β are two pathologic hallmarks of Alzheimer's disease. We
conducted an epigenome-wide association study using the histone 3 lysine 9 acetylation …

Amyotrophic lateral sclerosis (ALS) is a terminal neurodegenerative disease. Genetic
predisposition, epigenetic changes, aging and accumulated life-long environmental …

DNA methylation plays important roles in determining cellular identity, disease, and
environmental responses, but little is known about the mechanisms that drive methylation …

Rheumatoid arthritis is an immune-mediated disease that primarily affects diarthrodial joints.
Susceptibility and severity of this disease are influenced by nongenetic factors, such as …

In this systematic review, we highlight the differences between the male and female
zebrafish brains to understand their differentiation and their use in studying sex-specific …

Klotho was first discovered as an anti-ageing protein linked to a number of age-related
disease processes, including cardiovascular, renal, musculoskeletal, and …

The field of neurodegenerative disease research has seen tremendous advances over the
last two decades as new technologies and analytic methods have enabled well-powered …

Mounting evidence has called into question our understanding of the role that the central
dogma of molecular biology plays in human pathology. The conventional view that …