Proteomic profiling of ovarian clear cell carcinomas identifies prognostic biomarkers for chemotherapy

L Yue, T Gong, W Jiang, L Qian, W Gong, Y Sun… - …, 2024 - Wiley Online Library
Clear cell ovarian carcinoma (CCOC) is a relatively rare subtype of ovarian cancer (OC) with
high degree of resistance to standard chemotherapy. Little is known about the underlying …

Missing value imputation using XGboost for label-free mass spectrometry-based proteomics data

J Song, C Yu - BioRxiv, 2021 - biorxiv.org
The label-free mass spectrometry-based proteomics data inevitably suffer from the problem
of missing values. The existence of missing values prevents the downstream analyses which …

T cell receptor engineered lymphocytes for cancer therapy

MR Rollins, EJ Spartz… - Current protocols in …, 2020 - Wiley Online Library
T lymphocytes are capable of specific recognition and elimination of target cells.
Physiological antigen recognition is mediated by the T cell receptor (TCR), which is an alpha …

[HTML][HTML] Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways

M Meng, Y Guo, Y Chen, X Li, B Zhang, Z Xie, J Liu… - Cellular Oncology, 2023 - Springer
Background Cancer/testis antigen-45A1 (CT45A1) is overexpressed in various types of
cancer but is not expressed in healthy women. The role of CT45A1 in cervical cancer has …

[HTML][HTML] The Cancer/Testis Antigen CT45A1 Promotes Transcription of Oncogenic Sulfatase-2 Gene in Breast Cancer Cells and Is Sensible Targets for Cancer …

P Yang, Y Qiao, H Liao, Y Huang, M Meng… - Journal of Breast …, 2023 - ncbi.nlm.nih.gov
Purpose Invasive breast carcinomas (BRCAs) are highly lethal. The molecular mechanisms
underlying progression of invasive BRCAs are unclear, and effective therapies are highly …

[HTML][HTML] Role and clinical utility of cancer/testis antigens in head and neck squamous cell carcinoma

SC Wu, K Münger - Cancers, 2021 - mdpi.com
Simple Summary In this review, we discuss the roles of cancer/testis antigens in the
germline and their contributions to oncogenic cellular processes. Specifically, we focus on …

Integrated strategy for discovery and validation of glycated candidate biomarkers for hemodialysis patients with cardiovascular complications

L Wu, C Fang, L Zhang, W Yuan, X Yu… - Analytical Chemistry, 2021 - ACS Publications
Glycation plays a pathogenic role in many age-related degenerative pathological conditions,
such as diabetes, end-stage renal diseases, and cardiovascular diseases. Mass …

Neuromuscular disorders in the omics era

I Dabaj, F Ducatez, S Marret, S Bekri, A Tebani - Clinica Chimica Acta, 2023 - Elsevier
Neuromuscular disorders encompass a spectrum of conditions characterized by primary
lesions within the peripheral nervous system, which include the anterior horn cell, peripheral …

[HTML][HTML] Altered genome‑wide hydroxymethylation analysis for neoadjuvant chemoradiotherapy followed by surgery in esophageal cancer

X Zhang, M Lu, J Zhu, C Zhang… - Experimental and …, 2023 - spandidos-publications.com
Esophageal cancer has high incidence rate in China. Neoadjuvant chemoradiotherapy
(nCRT) has become the standard treatment for esophageal squamous cell carcinoma …

[HTML][HTML] Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold …

Y Xiong, S Li, Y Bai, T Chen, W Sun, L Chen… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Psoriasis, a complex and recurrent chronic inflammatory skin disease involving various
inflammatory cell types, requires effective cell communication to maintain the homeostatic …