Despite thousands of articles about 5-methylcytosine (m5C) residues in vertebrate DNA,
there is still controversy concerning the role of genomic m5C in normal vertebrate …

A major challenge in biology is to understand how genetic information is interpreted to direct
the formation of specialized tissues within a multicellular organism. During differentiation …

Objective To determine whether changes in the DNA methylation status in the promoter
region of the gene encoding interleukin‐1β (IL‐1β) account for expression of IL1B …

A meta-analysis of whole-genome linkage scans confirmed linkage between schizophrenia
and markers on the long arm of chromosome 13. The gene HTR2A, which codes for the …

Isoflavones are phytoestrogens that have been linked to both beneficial as well as adverse
effects in relation to cell proliferation and cancer risks. The present article presents an …

Osteolytic lesions in multiple myeloma are caused by osteoclast-mediated bone resorption
and reduced bone formation. A unique feature of myeloma is a failure of bone healing after …

Epigenetic modifications in plants can be directed and mediated by small RNAs (sRNAs).
This regulation is composed of a highly interactive network of sRNA-directed DNA …

Increasing evidence suggests that epigenetic factors have critical roles in gene regulation in
neuropsychiatric disorders and in aging, both of which are typically associated with a wide …

SERine Protein INhibitor-A1 (SERPINA1) is an inducible blood cell gene coding for alpha1-
antitrypsin (AAT), a plasma protease inhibitor whose circulating levels are raised during …

Despite the remarkable progress achieved in the treatment of leukemias over the last
several years, many problems (multidrug resistance [MDR], cellular heterogeneity …