The programming power of the placenta

AN Sferruzzi-Perri, EJ Camm - Frontiers in physiology, 2016 - frontiersin.org
Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …

[HTML][HTML] Prenatal psychological or metabolic stress increases the risk for psychiatric disorders: the “funnel effect” model

C Musillo, A Berry, F Cirulli - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

Maternal microbiome disturbance induces deficits in the offspring's behaviors: a systematic review and meta-analysis

L Hassib, CL de Oliveira, GA Rouvier, A Kanashiro… - Gut …, 2023 - Taylor & Francis
Recent evidence has suggested that changes in maternal gut microbiota in early life may
generate neurobiological consequences associated with psychiatric-related abnormalities …

Parent–offspring cannibalism throughout the animal kingdom: a review of adaptive hypotheses

APH Bose - Biological Reviews, 2022 - Wiley Online Library
Parents that kill and consume their offspring often appear to be acting against their own
reproductive interests. Yet parent–offspring cannibalism is common and taxonomically …

Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review

L Kong, X Chen, M Gissler, C Lavebratt - International Journal of …, 2020 - nature.com
Obesity and diabetes is a worldwide public health problem among women of reproductive
age. This narrative review highlights recent epidemiological studies regarding associations …

Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity

C Musillo, KC Creutzberg, B Collacchi… - Translational …, 2023 - nature.com
Maternal obesity has been recognized as a stressor affecting the developing fetal brain,
leading to long-term negative outcomes comparable to those resulting from maternal …

Maternal flavonoids intake reverts depression-like behaviour in rat female offspring

AL de la Garza, MA Garza-Cuellar, IA Silva-Hernandez… - Nutrients, 2019 - mdpi.com
Maternal hypercaloric exposure during pregnancy and lactation is a risk factor for
developing diseases associated with inflammation such as obesity, diabetes and …

Maternal and early-life circadian disruption have long-lasting negative consequences on offspring development and adult behavior in mice

BL Smarr, AD Grant, L Perez, I Zucker, LJ Kriegsfeld - Scientific Reports, 2017 - nature.com
Modern life involves chronic circadian disruption through artificial light and these disruptions
are associated with numerous mental and physical health maladies. Because the …

Maternal high-fat diet leads to hippocampal and amygdala dendritic remodeling in adult male offspring

Y Janthakhin, M Rincel, AM Costa… - …, 2017 - Elsevier
Early-life exposure to calorie-dense food, rich in fat and sugar, contributes to the increasing
prevalence of obesity and its associated adverse cognitive and emotional outcomes at …

Neurobiological mechanisms modulating emotionality, cognition and reward-related behaviour in high-fat diet-fed rodents

D Ziemens, C Touma, V Rappeneau - International journal of molecular …, 2022 - mdpi.com
Affective and substance-use disorders are associated with overweight and obesity-related
complications, which are often due to the overconsumption of palatable food. Both high-fat …