Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction
H Pellegrini, EH Sharpe, G Liu, E Nishiuchi… - Journal of Biological …, 2023 - ASBMB
Mutations in the gene encoding polycystin-1 (PC1) are the most common cause of
autosomal dominant polycystic kidney disease (ADPKD). Cysts in ADPKD exhibit a Warburg …
autosomal dominant polycystic kidney disease (ADPKD). Cysts in ADPKD exhibit a Warburg …
TRPV4 functional status in cystic cells regulates cystogenesis in autosomal recessive polycystic kidney disease during variations in dietary potassium
K Pyrshev, A Stavniichuk, VN Tomilin… - Physiological …, 2023 - Wiley Online Library
Mechanosensitive TRPV4 channel plays a dominant role in maintaining [Ca2+] i
homeostasis and flow‐sensitive [Ca2+] i signaling in the renal tubule. Polycystic kidney …
homeostasis and flow‐sensitive [Ca2+] i signaling in the renal tubule. Polycystic kidney …
Modelling genetic polycystic kidney disease using human pluripotent stem cell-derived kidney organoids
M Liu - 2023 - dr.ntu.edu.sg
Polycystic kidney disease (PKD) is an inherited disorder characterized by progressive
expansion of fluid-filled cysts in the kidney. Autosomal dominant polycystic kidney disease …
expansion of fluid-filled cysts in the kidney. Autosomal dominant polycystic kidney disease …