[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
DNA methylation plays a vital role in epigenetic regulation in both plants and animals, and
typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …

[HTML][HTML] Studies of the Mechanism of Nucleosome Dynamics: A Review on Multifactorial Regulation from Computational and Experimental Cases

D Shi, Y Huang, C Bai - Polymers, 2023 - mdpi.com
The nucleosome, which organizes the long coil of genomic DNA in a highly condensed,
polymeric way, is thought to be the basic unit of chromosomal structure. As the most …

Asymmetric Periodic Boundary Conditions for All-Atom Molecular Dynamics and Coarse-Grained Simulations of Nucleic Acids

R Erban, Y Togashi - The Journal of Physical Chemistry B, 2023 - ACS Publications
Periodic boundary conditions are commonly applied in molecular dynamics simulations in
the microcanonical (NVE), canonical (NVT), and isothermal–isobaric (NpT) ensembles. In …

Molecular dynamics analysis of biomolecular systems including nucleic acids

T Kameda, A Awazu, Y Togashi - Biophysics and Physicobiology, 2022 - jstage.jst.go.jp
With the recent progress in structural biology and genome biology, structural dynamics of
molecular systems that include nucleic acids has attracted attention in the context of gene …

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

M Balzarolo, S Engels, AJ de Jong… - Open …, 2021 - royalsocietypublishing.org
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition
of microbial infections. Microbial DNA is frequently methylated at the N6 position of adenines …