In recent decades, the worldwide prevalence of obesity has risen dramatically and is
currently estimated to be around 20%. Obesity is linked to an increased risk of comorbidities …

Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

Infertility affects nearly 186 million people worldwide and the male partner is the cause in
about half of the cases. Meta-regression data indicate an unexplained decline in sperm …

Background: In the last 40 years, assisted reproductive techniques (ARTs) have emerged as
potentially resolving procedures for couple infertility. This study aims to evaluate whether …

This systematic review and meta-analysis summarize the difference in the methylation of the
H19 gene in patients with abnormal versus normal conventional sperm parameters. It also …

Assisted reproductive technology may influence epigenetic signature as the procedures
coincide with the extensive epigenetic modification occurring from fertilization to embryo …

Recurrent spontaneous abortion (RSA) is a highly heterogeneous complication of
pregnancy with the underlying mechanisms remaining uncharacterized. Dysregulated …

The dramatic rise in obesity has recently made it a global health issue. About 1.9 billion
were overweight, and 650 million global populations were obese in 2016. Obese women …

Introduction Insulin-like growth factor 2 (IGF2) mRNA has been found in human and mouse
spermatozoa. It is currently unknown whether the IGF2 protein is expressed in human …

The characteristic of obesity is body fat accumulation in excess, which has a deteriorating
effect on human health. Almost 650 million individuals are obese, while 1.9 billion people …