[HTML][HTML] iSEE: interactive summarizedexperiment explorer

K Rue-Albrecht, F Marini, C Soneson, ATL Lun - F1000Research, 2018 - ncbi.nlm.nih.gov
Data exploration is critical to the comprehension of large biological data sets generated by
high-throughput assays such as sequencing. However, most existing tools for interactive …

[HTML][HTML] Variability of multi-omics profiles in a population-based child cohort

M Gallego-Paüls, C Hernández-Ferrer, M Bustamante… - BMC medicine, 2021 - Springer
Background Multiple omics technologies are increasingly applied to detect early, subtle
molecular responses to environmental stressors for future disease risk prevention. However …

[HTML][HTML] Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

AJ Stevenson, DL McCartney, RF Hillary… - Clinical …, 2020 - Springer
Background Chronic systemic inflammation has been associated with incident dementia, but
its association with age-related cognitive decline is less clear. The acute responses of many …

[HTML][HTML] Epigenetic signatures of starting and stopping smoking

DL McCartney, AJ Stevenson, RF Hillary, RM Walker… - …, 2018 - thelancet.com
Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …

[HTML][HTML] Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder

S Hesam-Shariati, BJ Overs, G Roberts, C Toma… - Translational …, 2022 - nature.com
Environmental factors contribute to risk of bipolar disorder (BD), but how environmental
factors impact the development of psychopathology within the context of elevated genetic …

[HTML][HTML] The early-life exposome modulates the effect of polymorphic inversions on DNA methylation

N Carreras-Gallo, A Cáceres, L Balagué-Dobón… - Communications …, 2022 - nature.com
Polymorphic genomic inversions are chromosomal variants with intrinsic variability that play
important roles in evolution, environmental adaptation, and complex traits. We investigated …

[HTML][HTML] Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children's blood

C Ruiz-Arenas, C Hernandez-Ferrer, M Vives-Usano… - Elife, 2022 - elifesciences.org
Background: The identification of expression quantitative trait methylation (eQTMs), defined
as associations between DNA methylation levels and gene expression, might help the …

[HTML][HTML] Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

F Marabita, M Almgren, LK Sjöholm, L Kular, Y Liu… - Scientific reports, 2017 - nature.com
Cigarette smoking is an established environmental risk factor for Multiple Sclerosis (MS), a
chronic inflammatory and neurodegenerative disease, although a mechanistic basis …

[HTML][HTML] Epigenome-wide analysis of maternal exposure to green space during gestation and cord blood DNA methylation in the ENVIRONAGE cohort

R Alfano, E Bijnens, SAS Langie, TS Nawrot… - Environmental …, 2023 - Elsevier
Background DNA methylation programming is sensitive to prenatal life environmental
influences, but the impact of maternal exposure to green space on newborns DNA …

[HTML][HTML] DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

X Shen, D Caramaschi, MJ Adams, RM Walker… - Genome medicine, 2022 - Springer
Background Depression is a disabling and highly prevalent condition where genetic and
epigenetic, such as DNA methylation (DNAm), differences contribute to disease risk. DNA …