[HTML][HTML] iSEE: interactive summarizedexperiment explorer
Data exploration is critical to the comprehension of large biological data sets generated by
high-throughput assays such as sequencing. However, most existing tools for interactive …
high-throughput assays such as sequencing. However, most existing tools for interactive …
[HTML][HTML] Variability of multi-omics profiles in a population-based child cohort
M Gallego-Paüls, C Hernández-Ferrer, M Bustamante… - BMC medicine, 2021 - Springer
Background Multiple omics technologies are increasingly applied to detect early, subtle
molecular responses to environmental stressors for future disease risk prevention. However …
molecular responses to environmental stressors for future disease risk prevention. However …
[HTML][HTML] Characterisation of an inflammation-related epigenetic score and its association with cognitive ability
Background Chronic systemic inflammation has been associated with incident dementia, but
its association with age-related cognitive decline is less clear. The acute responses of many …
its association with age-related cognitive decline is less clear. The acute responses of many …
[HTML][HTML] Epigenetic signatures of starting and stopping smoking
Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
[HTML][HTML] Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder
Environmental factors contribute to risk of bipolar disorder (BD), but how environmental
factors impact the development of psychopathology within the context of elevated genetic …
factors impact the development of psychopathology within the context of elevated genetic …
[HTML][HTML] The early-life exposome modulates the effect of polymorphic inversions on DNA methylation
Polymorphic genomic inversions are chromosomal variants with intrinsic variability that play
important roles in evolution, environmental adaptation, and complex traits. We investigated …
important roles in evolution, environmental adaptation, and complex traits. We investigated …
[HTML][HTML] Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children's blood
C Ruiz-Arenas, C Hernandez-Ferrer, M Vives-Usano… - Elife, 2022 - elifesciences.org
Background: The identification of expression quantitative trait methylation (eQTMs), defined
as associations between DNA methylation levels and gene expression, might help the …
as associations between DNA methylation levels and gene expression, might help the …
[HTML][HTML] Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship
Cigarette smoking is an established environmental risk factor for Multiple Sclerosis (MS), a
chronic inflammatory and neurodegenerative disease, although a mechanistic basis …
chronic inflammatory and neurodegenerative disease, although a mechanistic basis …
[HTML][HTML] Epigenome-wide analysis of maternal exposure to green space during gestation and cord blood DNA methylation in the ENVIRONAGE cohort
Background DNA methylation programming is sensitive to prenatal life environmental
influences, but the impact of maternal exposure to green space on newborns DNA …
influences, but the impact of maternal exposure to green space on newborns DNA …
[HTML][HTML] DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses
Background Depression is a disabling and highly prevalent condition where genetic and
epigenetic, such as DNA methylation (DNAm), differences contribute to disease risk. DNA …
epigenetic, such as DNA methylation (DNAm), differences contribute to disease risk. DNA …