Differences of DNA methylation patterns in the placenta of large for gestational age infant

Z Shen, Y Tang, Y Song, W Shen, C Zou - Medicine, 2020 - journals.lww.com
Differences of DNA methylation patterns in the placenta of l... : Medicine Differences of DNA
methylation patterns in the placenta of large for gestational age infant : Medicine Log in or …

[HTML][HTML] Addressing Modern Diagnostic Pathology for Patient-Derived Soft Tissue Sarcosphere Models in the Era of Functional Precision Oncology

Y Chen, M Herzog, A Pliego-Mendieta, MM Bühler… - Laboratory …, 2023 - Elsevier
Responses to therapy often cannot be exclusively predicted by molecular markers, thus
evidencing a critical need to develop tools for better patient selection based on relations …

[HTML][HTML] Association of self-identified race and genetic ancestry with the immunogenomic landscape of primary prostate cancer

T Vidotto, EL Imada, F Faisal, S Murali, AA Mendes… - JCI insight, 2023 - ncbi.nlm.nih.gov
The genomic and immune landscapes of prostate cancer differ by self-identified race.
However, few studies have examined the genome-wide copy number landscape and …

Sperm DNA methylome abnormalities occur both pre-and post-treatment in men with Hodgkin disease and testicular cancer

D Chan, K Oros Klein, A Riera-Escamilla, C Krausz… - Clinical …, 2023 - Springer
Background Combination chemotherapy has contributed to increased survival from Hodgkin
disease (HD) and testicular cancer (TC). However, questions concerning the quality of …

Meffil: efficient normalisation and analysis of very large DNA methylation samples

J Min, G Hemani, GD Smith, C Relton, M Suderman - bioRxiv, 2017 - biorxiv.org
Background Technological advances in high throughput DNA methylation microarrays have
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …

Novel DNA methylome biomarkers associated with adalimumab response in rheumatoid arthritis patients

I Hageman, F Mol, S Atiqi, V Joustra, H Sengul… - Frontiers in …, 2023 - frontiersin.org
Background and aims Rheumatoid arthritis (RA) patients are currently treated with biological
agents mostly aimed at cytokine blockade, such as tumor necrosis factor-alpha (TNFα) …

Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns

HP Santos Jr, AE Enggasser, J Clark, K Roell… - BMC biology, 2023 - Springer
Background Health outcomes among children born prematurely are known to be sexually
dimorphic, with male infants often more affected, yet the mechanism behind this observation …

Derivation of poly-methylomic profile scores for schizophrenia

OJ Watkeys, S Cohen-Woods, Y Quidé… - Progress in Neuro …, 2020 - Elsevier
Schizophrenia and bipolar disorder share biological features and environmental risk factors
that may be associated with altered DNA methylation. In this study we sought to: 1) construct …

Accelerated epigenetic ageing in major depressive disorder

HC Whalley, J Gibson, R Marioni, RM Walker… - BioRxiv, 2017 - biorxiv.org
Background Major depressive disorder (MDD) is a severe, heritable psychiatric disorder
associated with shortened lifespan and comorbidities of advancing age. It is unknown …

Genome-wide methylation data improves dissection of the effect of smoking on body mass index

C Amador, Y Zeng, M Barber, RM Walker… - PLoS …, 2021 - journals.plos.org
Variation in obesity-related traits has a genetic basis with heritabilities between 40 and 70%.
While the global obesity pandemic is usually associated with environmental changes related …