Background The identification of expression quantitative trait methylation (eQTMs), defined
as associations between DNA methylation levels and gene expression, might help the …

Telomere length at birth determines later life telomere length and potentially predicts ageing-
related diseases. However, the genetic and epigenetic settings of telomere length in …

Epigenetic clocks provide powerful tools for estimating health and lifespan but their ability to
predict brain degeneration and neuronal damage during the aging process is unknown. In …

dc. description. abstract Bipolar disorder (BD) is a complex mental illness for which both
environmental and biological (genetic and epigenetic) factors play an aetiological role. This …

Variation in the rate at which humans age may be rooted in early life events acting through
genomic regions that are influenced by such events and subsequently are related to health …

Variation in complex traits related to obesity, such as body weight and body mass index, has
a genetic basis with heritabilities between 40 and 70%. Nonetheless, the so-called global …

SNPs in ABCA7 confer the largest genetic risk for Alzheimer's Disease (AD) in African
Americans (AA) after APOE ε4. However, the relationship between ABCA7 and cognitive …

Krüppel-associated box zinc finger proteins (KRAB-ZFPs) are the largest gene family of
transcriptional regulators in higher vertebrates. We have developed a method for inferring …

Epigenome-wide Association Studies (EWAS) have been a popular method to investigate
the genome over the past decade. From these experiments, more than 75,000 samples have …

DNA methylation analysis displays considerable promise in forensic applications offering
additional information to traditional DNA profiling techniques. This research assesses the …