Hypoxic-ischemic encephalopathy (HIE) is a complex pathophysiological process with
multiple links and factors. It involves the interaction of inflammation, oxidative stress, and …

Birth asphyxia and its main sequel, hypoxic-ischemic encephalopathy, are one of the
leading causes of children's deaths worldwide and can potentially worsen the quality of life …

Background: Neonatal hypoxia-ischemia encephalopathy (HIE) is the leading cause of
neonatal death and poor neurodevelopmental outcomes worldwide. Therapeutic …

OBJECTIVE Therapeutic hypothermia reduces the risk of death and major disability in
neonates with moderate-to-severe hypoxic ischemic encephalopathy (HIE). Opioids and …

BACKGROUND: Sedation is recommended to optimize neuroprotection in neonates with
hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH) …

Introduction Neonatal hypoxic–ischemic brain damage (HIBD) is a serious inflammatory
injury. At present, the standard treatment for this disease is hypothermia therapy, and the …

Objective Classification of electroencephalogram (EEG) background has been established
to predict outcome in neonates with hypoxic ischemic encephalopathy (HIE). However, the …

Background Neonatal encephalopathy (NE) remains a common cause of infant morbidity
and mortality. Neuropathological corollaries of NE associated with acute hypoxia-ischemia …

After perinatal asphyxia, hypoxic-ischemic encephalopathy (HIE) in term infants produces
long-term neurologic sequelae or death. Obtaining a reliable, evidence-based prognosis is …

Introduction Hospitalizations of high-risk infants are among the most expensive in the United
States, with many requiring surgery and months of intensive care. Healthcare costs and …