Transcription factors are key determinants of gene expression that recognize and bind to
short DNA sequence motifs, thereby regulating many biological processes including …

Fully differentiated pancreatic β cells are essential for normal glucose homeostasis in
mammals. Dedifferentiation of these cells has been suggested to occur in type 2 diabetes …

Background In vitro follicle culture (IFC), as applied in the mouse system, allows the growth
and maturation of a large number of immature preantral follicles to become mature and …

Abstract Background Bisphenol S (BPS) is a common bisphenol A (BPA) substitute, since
BPA is virtually banned worldwide. However, BPS and BPA have both endocrine disrupting …

Aberrant methylation of Nr4a3 exon 3 CpG island (CpGi) was initially identified during
multistep mouse skin carcinogenesis. Nr4a3 is also known as a critical gene for neuronal …

Background: DNA methylation is an important epigenetic modification that affects genomic
instability and regulates gene expression. Long non-coding RNAs (lncRNAs) modulate …

Background Hepatocellular carcinoma (HCC) is one of the most common human
malignancies in the world, and its prognosis is generally poor. Epigenetic alteration such as …

Background The identification of tissue‐specific differentially methylated regions (tDMRs) is
key to our understanding of mammalian development. Research has indicated that tDMRs …

Résumé Les phénomènes de méthylation/déméthylation de l'ADN sont des pièces
maîtresses du maintien et de la régulation du génome. Ces modifications chimiques, qui …

Les neuroblastomes olfactifs (NBOs) sont des tumeurs rares de la base du crâne. Les outils
de classification de ces tumeurs sont insuffisants, il n'existe notamment aucune classification …