Infertility has become a major health issue in the world. It affects the social life of couples
and of all infertility cases; approximately 40–50% is due to “male factor” infertility. Male …

We are entering an exciting epoch in livestock biotechnology during which the fundamental
approaches (such as transgenesis, spermatozoa cryopreservation and artificial …

Even though cryopreservation of human spermatozoa is known to alter sperm motility and
viability, it may also induce nuclear damages. The present study set out to determine …

Swine testicular (ST) cell line is isolated from swine fetal testes and has been widely used in
biomedical research fields related to pig virus infection. However, the potential benefit and …

Bisphenol A (BPA) is an endocrine disruptor that negatively affects spermatogenesis, a
process where Sertoli cells play a central role. Thus, in the present study we sought to …

Understanding the mechanisms that lead to the differentiation of male germ cells from their
spermatogonial stem cells through meiosis to give rise to mature haploid spermatozoa has …

Several lines of evidence suggest that insulin-like growth factor 1 (IGF1) is involved in Sertoli
cell (SC) proliferation and that its receptor (IGF1R) could mediate follicle-stimulating …

Because Sertoli cells (SCs) play a central role in germ cell survival, their death may result in
marked germ cell loss and infertility. SCs are the only somatic cells within the seminiferous …

At present, there is no reliable in vitro assembled prepubertal testis-like biomimetic organ
culture system designed to assess the functional effects of human gonadotropins on Sertoli …

Sertoli cells (SC) are a type of important cells in the testes, which can provide transport
proteins, regulatory proteins, growth factors, and other cytokines for the spermatogenic …