Chromatin accessibility profiling methods

L Minnoye, GK Marinov, T Krausgruber, L Pan… - Nature Reviews …, 2021 - nature.com
Chromatin accessibility, or the physical access to chromatinized DNA, is a widely studied
characteristic of the eukaryotic genome. As active regulatory DNA elements are generally …

[HTML][HTML] Inferring interaction networks from multi-omics data

JS Hawe, FJ Theis, M Heinig - Frontiers in genetics, 2019 - frontiersin.org
A major goal in systems biology is a comprehensive description of the entirety of all complex
interactions between different types of biomolecules—also referred to as the interactome …

ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments

F Hammal, P De Langen, A Bergon… - Nucleic acids …, 2022 - academic.oup.com
Abstract ReMap (https://remap. univ-amu. fr) aims to provide manually curated, high-quality
catalogs of regulatory regions resulting from a large-scale integrative analysis of DNA …

The UCSC genome browser database: 2021 update

J Navarro Gonzalez, AS Zweig, ML Speir… - Nucleic acids …, 2021 - academic.oup.com
For more than two decades, the UCSC Genome Browser database (https://genome. ucsc.
edu) has provided high-quality genomics data visualization and genome annotations to the …

JASPAR 2020: update of the open-access database of transcription factor binding profiles

O Fornes, JA Castro-Mondragon, A Khan… - Nucleic acids …, 2020 - academic.oup.com
Abstract JASPAR (http://jaspar. genereg. net) is an open-access database of curated, non-
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …

[PDF][PDF] Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease

L Traxler, JR Herdy, D Stefanoni, S Eichhorner… - Cell Metabolism, 2022 - cell.com
The drivers of sporadic Alzheimer's disease (AD) remain incompletely understood. Utilizing
directly converted induced neurons (iNs) from AD-patient-derived fibroblasts, we identified a …

ChEA3: transcription factor enrichment analysis by orthogonal omics integration

AB Keenan, D Torre, A Lachmann… - Nucleic acids …, 2019 - academic.oup.com
Identifying the transcription factors (TFs) responsible for observed changes in gene
expression is an important step in understanding gene regulatory networks. ChIP-X …

The UCSC genome browser database: 2019 update

M Haeussler, AS Zweig, C Tyner, ML Speir… - Nucleic acids …, 2019 - academic.oup.com
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is a graphical viewer for
exploring genome annotations. For almost two decades, the Browser has provided …

Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis

R Zheng, C Wan, S Mei, Q Qin, Q Wu… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Cistrome Data Browser (DB) is a resource of human and mouse cis-regulatory
information derived from ChIP-seq, DNase-seq and ATAC-seq chromatin profiling assays …

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

A Khan, O Fornes, A Stigliani, M Gheorghe… - Nucleic acids …, 2018 - academic.oup.com
Abstract JASPAR (http://jaspar. genereg. net) is an open-access database of curated, non-
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …