[PDF][PDF] Oxidative stress and inflammatory markers in prediabetes and diabetes.

K Luc, A Schramm-Luc, TJ Guzik… - Journal of Physiology & …, 2019 - researchgate.net
Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …

The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

The global and regional prevalence of abdominal aortic aneurysms: a systematic review and modeling analysis

P Song, Y He, D Adeloye, Y Zhu, X Ye, Q Yi… - Annals of …, 2023 - journals.lww.com
Objective: To estimate the global and regional prevalence and cases of abdominal aortic
aneurysms (AAAs) in 2019 and to evaluate major associated factors. Background …

Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves

D Mauricio, M Gratacòs, J Franch-Nadal - Cardiovascular Diabetology, 2023 - Springer
Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by
structural and functional abnormalities within the intricate network of microvessels beyond …

JCS/JSCVS/JATS/JSVS 2020 guideline on diagnosis and treatment of aortic aneurysm and aortic dissection

H Ogino, O Iida, K Akutsu, Y Chiba, H Hayashi… - Circulation …, 2023 - jstage.jst.go.jp
Of the clinical practice guideline of the Japanese Circulation Society concerning aortic
diseases, the Guidelines on Diagnosis and Treatment of Aortic Dissection (first edition) were …

Novel pharmacological approaches in abdominal aortic aneurysm

L Puertas-Umbert, R Almendra-Pegueros… - Clinical …, 2023 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

Microfluidic and organ-on-a-chip approaches to investigate cellular and microenvironmental contributions to cardiovascular function and pathology

EL Doherty, WY Aw, AJ Hickey… - … in Bioengineering and …, 2021 - frontiersin.org
Over the past decade, advances in microfabrication and biomaterials have facilitated the
development of microfluidic tissue and organ models to address challenges with …

Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm

T Roychowdhury, H Lu, WE Hornsby, B Crone… - The American Journal of …, 2021 - cell.com
Thoracic aortic aneurysm (TAA) is characterized by dilation of the aortic root or
ascending/descending aorta. TAA is a heritable disease that can be potentially life …

Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel …

K Huang, Y Wang, KL Siu, Y Zhang, H Cai - Redox Biology, 2021 - Elsevier
In the present study we aimed to identify novel mechanisms and therapeutics for thoracic
aortic aneurysm (TAA) in Fbn1 C1039G/+ Marfan Syndrome (MFS) mice. The expression of …

Exploring the correlation and protective role of diabetes mellitus in aortic aneurysm disease

D Arun, W Munir, LV Schmitt, R Vyas… - Frontiers in …, 2021 - frontiersin.org
Introduction: Diabetes mellitus is recognised as a significant risk factor for cardiovascular
and peripheral vascular disease, as the abnormal metabolic state increases the risk for …