Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

Idiopathic pulmonary fibrosis (IPF) is a type of interstitial pneumonia characterized by
chronic and progressive fibrosis with an unknown etiology. Previous pharmacological …

Objective Excessive extra-cellular-matrix production and uncontrolled proliferation of the
fibroblasts are characteristics of many fibrotic diseases, including idiopathic pulmonary …

Desmoplastic reaction is a fibrosis reaction that is characterized by a large amount of dense
extracellular matrix (ECM) and dense fibrous stroma. Fibrotic stroma around the tumor has …

Background The targeted therapy for lung cancer relies on prognostic genes and requires
further research. No research has been conducted to determine the effect of endothelin …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible interstitial lung
disease with a prognosis worse than lung cancer. It is a fatal lung disease with largely …

Abstract Nickel oxide nanoparticles (Nano NiO) have been shown to cause pulmonary
fibrosis; But, the underlying epigenetic mechanisms remain poorly understood. In this study …

Epigenetic modifications are involved in fibrotic diseases, such as idiopathic pulmonary
fibrosis (IPF), and contribute to the silencing of anti‐fibrotic genes. H3K27me3, a key …

Background Based on the bioinformatics prediction, this study investigates the correlation
between aberrant transcription factor Frizzled 5 (FZD5) expression and the establishment of …