Autophagy is characterized by sequestration of bulk cytoplasm and organelles in double or
multimembrane autophagic vesicles, and their delivery to and subsequent degradation by …

The Death-Associated Protein kinase (DAPk) family contains three closely related
serine/threonine kinases, named DAPk, ZIPk and DRP-1, which display a high degree of …

Purpose Aberrant promoter hypermethylation of several known or putative tumor suppressor
genes occurs frequently during the pathogenesis of prostate cancers and is a promising …

Allelic losses on the chromosome arms 1p and 19q have been associated with favorable
response to chemotherapy and good prognosis in anaplastic oligodendroglioma patients …

The methylation status of the O6‐methylguanine‐methyltransferase promoter (MGMTP) was
evaluated in 68 low‐grade gliomas treated by neoadjuvant temozolomide. Methylated …

Purpose To date, no data are available on the relationship between 1p/19q deletions and
the response to temozolomide (TMZ) in primary anaplastic oligodendroglioma (AO) and …

Survival rates of pediatric brain tumor patients have significantly improved over the years
due to developments in diagnostic techniques, neurosurgery, chemotherapy, radiotherapy …

Background Methylation of the O 6-methylguanine-DNA methyltransferase (MGMT) gene
promoter is a favorable prognostic factor in glioblastoma patients. However, reported …

Pancreatic endocrine neoplasms are neoplastic proliferations of islet cells or islet cell
precursors and are capable of secreting a variety of synthetic products, including insulin …

Low-grade gliomas (LGGs) represent a vexing clinical problem. Some patients present with
readily controllable seizures and will enjoy years of freedom from tumor progression without …