Hypertension in aortic stenosis: a focused review and recommendations for clinical practice

S Saeed, F Scalise, JB Chambers… - Journal of …, 2020 - journals.lww.com
In patients with aortic stenosis, the presence of hypertension negatively affects the
hemodynamic severity of the stenosis, and worsens adverse left ventricular remodeling. It …

Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis

MA Nadir, L Wei, DHJ Elder, R Libianto, TK Lim… - Journal of the American …, 2011 - jacc.org
Objectives: The purpose of this study was to investigate the impact of renin-angiotensin
system blockade therapy on outcomes in aortic stenosis (AS). Background: Angiotensin …

The medical management of valvar heart disease

NA Boon, P Bloomfield - Heart, 2002 - heart.bmj.com
Although there is very little high quality evidence to guide the medical treatment of valve dis-
ease, this is an important area of cardiology for two reasons. Firstly, there are many frail …

Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function

KD O'Brien, XQ Zhao, DM Shavelle… - Journal of …, 2004 - journals.sagepub.com
Background Angiotensin-converting enzyme (ACE) inhibitor use is presumed to be
contraindicated in patients with aortic stenosis (AS). We determined the hemodynamic …

Renin–angiotensin system inhibition is not associated with increased sudden cardiac death, cardiovascular mortality or all-cause mortality in patients with aortic …

CN Bang, AM Greve, L Køber, AB Rossebø… - International journal of …, 2014 - Elsevier
Background Renin–angiotensin system inhibition (RASI) is frequently avoided in aortic
stenosis (AS) patients because of fear of hypotension. We evaluated if RASI with …

Survival benefits of angiotensin‐converting enzyme inhibitors in older heart failure patients with perceived contraindications

A Ahmed, CI Kiefe, RM Allman… - Journal of the …, 2002 - Wiley Online Library
OBJECTIVES: To determine the association between angiotensin‐converting enzyme (ACE)
inhibitor therapy and survival of older heart failure patients with conditions perceived by …

ACE inhibition in aortic stenosis: dangerous medicine or golden opportunity?

HC Routledge, JN Townend - Journal of human hypertension, 2001 - nature.com
Conventionally angiotensin-converting enzyme (ACE) inhibitors are contraindicated in
patients with aortic stenosis. Abundant evidence is now available showing that angiotensin II …

Effects of angiotensin converting enzyme inhibitors in hypertensive patients with aortic valve stenosis: a drug withdrawal study

J Jimenez-Candil, J Bermejo, R Yotti, C Cortina… - Heart, 2005 - heart.bmj.com
Objective: To determine the effects of angiotensin converting enzyme (ACE) inhibitors in
hypertensive patients with aortic valve stenosis (AS). Design: Observational, drug …

Is blockade of the Renin-Angiotensin system able to reverse the structural and functional remodeling of the left ventricle in severe aortic stenosis?

S Helske-Suihko, M Laine, J Lommi… - Journal of …, 2015 - journals.lww.com
In experimental aortic stenosis (AS), blockade of the renin-angiotensin system attenuates AS-
related left ventricular (LV) dysfunction and improves survival. We tested whether …

A propensity score analysis of the impact of angiotensin-converting enzyme inhibitors on long-term survival of older adults with heart failure and perceived …

A Ahmed, RM Centor, MT Weaver, GJ Perry - American heart journal, 2005 - Elsevier
OBJECTIVES: The purpose of this study is to determine the association between discharge
use of angiotensin-converting enzyme (ACE) inhibitors in patients with perceived …