Pathophysiology of GvHD and other HSCT-related major complications
S Ghimire, D Weber, E Mavin, XN Wang… - Frontiers in …, 2017 - frontiersin.org
For over 60 years, hematopoietic stem cell transplantation has been the major curative
therapy for several hematological and genetic disorders, but its efficacy is limited by the …
therapy for several hematological and genetic disorders, but its efficacy is limited by the …
[HTML][HTML] Defibrotide: properties and clinical use of an old/new drug
R Pescador, L Capuzzi, M Mantovani, A Fulgenzi… - Vascular …, 2013 - Elsevier
The drug named defibrotide (DFT) has been studied for many years. It has been shown to
possess many activities: profibrinolytic, antithrombotic–thrombolytic, antiischemic (heart …
possess many activities: profibrinolytic, antithrombotic–thrombolytic, antiischemic (heart …
Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults
Transplant-associated thrombotic microangiopathy (TMA) leads to generalized endothelial
dysfunction that can progress to multiorgan injury, and severe cases are associated with …
dysfunction that can progress to multiorgan injury, and severe cases are associated with …
Renal arteriolar C4d deposition: a novel characteristic of hematopoietic stem cell transplantation–associated thrombotic microangiopathy
BL Laskin, J Maisel, J Goebel, HJ Yin, G Luo… - …, 2013 - journals.lww.com
Background The mechanism of kidney injury in hematopoietic stem cell transplantation
(HSCT)–associated thrombotic microangiopathy (TA-TMA) is not completely understood …
(HSCT)–associated thrombotic microangiopathy (TA-TMA) is not completely understood …
Complement-mediated thrombotic microangiopathy as a link between endothelial damage and steroid-refractory GVHD
SA Wall, Q Zhao, M Yearsley, L Blower… - Blood …, 2018 - ashpublications.org
Transplant-associated thrombotic microangiopathy (TA-TMA), a complication of
hematopoietic cell transplant (HCT), is associated with significant morbidity and mortality …
hematopoietic cell transplant (HCT), is associated with significant morbidity and mortality …
Eculizumab for transplant‐associated thrombotic microangiopathy in adult allogeneic stem cell transplant recipients
J Rudoni, A Jan, C Hosing, F Aung… - European Journal of …, 2018 - Wiley Online Library
Objective To evaluate response rates and survival in adults with transplant‐associated
thrombotic microangiopathy (TA‐TMA) after allogeneic hematopoietic stem cell …
thrombotic microangiopathy (TA‐TMA) after allogeneic hematopoietic stem cell …
The effectiveness of ruxolitinib for acute/chronic graft-versus-host disease in children: a retrospective study
W Yang, G Zhu, M Qin, Z Li, B Wang… - Drug Design …, 2021 - Taylor & Francis
Objective This study aimed to evaluate the effectiveness of Ruxolitinib for acute/chronic graft-
versus-host disease in children. Methods This study was a retrospective trial. We analyzed …
versus-host disease in children. Methods This study was a retrospective trial. We analyzed …
TMA in kidney transplantation
Z Imanifard, L Liguori, G Remuzzi - Transplantation, 2023 - journals.lww.com
Thrombotic microangiopathy (TMA) is a rare and devastating complication of kidney
transplantation, which often leads to graft failure. Posttransplant TMA (PT-TMA) may occur …
transplantation, which often leads to graft failure. Posttransplant TMA (PT-TMA) may occur …
Thrombotic microangiopathy following haematopoietic stem cell transplant
EG Seaby, RD Gilbert - Pediatric Nephrology, 2018 - Springer
Thrombotic microangiopathy is a potentially lethal complication of haematopoietic stem cell
(bone marrow) transplantation. The pathophysiology is incompletely understood, although …
(bone marrow) transplantation. The pathophysiology is incompletely understood, although …
Hematopoietic stem cell transplantation and acute kidney injury in children: A comprehensive review
R Raina, N Herrera, V Krishnappa… - Pediatric …, 2017 - Wiley Online Library
AKI in the setting of HSCT is commonly investigated among adult patients. In the same way,
malignancies requiring treatment with HSCT are not limited to the adult patient population …
malignancies requiring treatment with HSCT are not limited to the adult patient population …