DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

DNA methylation is one of the best characterized epigenetic modifications. In mammals it is
involved in various biological processes including the silencing of transposable elements …

We have developed a new generation of genome-wide DNA methylation BeadChip which
allows high-throughput methylation profiling of the human genome. The new high density …

DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …

Aims: Studies of DNA methylomes hold enormous promise for biomedicine but are
hampered by the technological challenges of analyzing many samples cost-effectively …

It is now well established that the genomic landscape of DNA methylation (DNAm) gets
altered as a function of age, a process we here call 'epigenetic drift'. The biological …

Background Recently, DNA methylation was proposed to regulate fleshy fruit ripening.
Fleshy fruits can be distinguished by their ripening process as climacteric fruits, such as …

DNA methylation is a significant regulator of gene expression, and its role in carcinogenesis
recently has been a subject of remarkable interest. The aim of this review is to analyze the …

Background Recently, it has been proposed that epigenetic variation may contribute to the
risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic …

Aberrant DNA methylation is associated with cancer development and progression. There
are several types of specimens from which DNA methylation pattern can be measured and …