[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
DNA methylation in mammals
E Li, Y Zhang - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
DNA methylation is one of the best characterized epigenetic modifications. In mammals it is
involved in various biological processes including the silencing of transposable elements …
involved in various biological processes including the silencing of transposable elements …
[HTML][HTML] High density DNA methylation array with single CpG site resolution
M Bibikova, B Barnes, C Tsan, V Ho, B Klotzle, JM Le… - Genomics, 2011 - Elsevier
We have developed a new generation of genome-wide DNA methylation BeadChip which
allows high-throughput methylation profiling of the human genome. The new high density …
allows high-throughput methylation profiling of the human genome. The new high density …
SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips
DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …
normal development and frequently disrupted in disease. The Illumina …
Evaluation of the Infinium Methylation 450K technology
S Dedeurwaerder, M Defrance, E Calonne, H Denis… - …, 2011 - Taylor & Francis
Aims: Studies of DNA methylomes hold enormous promise for biomedicine but are
hampered by the technological challenges of analyzing many samples cost-effectively …
hampered by the technological challenges of analyzing many samples cost-effectively …
Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
It is now well established that the genomic landscape of DNA methylation (DNAm) gets
altered as a function of age, a process we here call 'epigenetic drift'. The biological …
altered as a function of age, a process we here call 'epigenetic drift'. The biological …
Downregulation of RdDM during strawberry fruit ripening
Background Recently, DNA methylation was proposed to regulate fleshy fruit ripening.
Fleshy fruits can be distinguished by their ripening process as climacteric fruits, such as …
Fleshy fruits can be distinguished by their ripening process as climacteric fruits, such as …
DNA methylation and cancer development: molecular mechanism
H Akhavan-Niaki, AA Samadani - Cell biochemistry and biophysics, 2013 - Springer
DNA methylation is a significant regulator of gene expression, and its role in carcinogenesis
recently has been a subject of remarkable interest. The aim of this review is to analyze the …
recently has been a subject of remarkable interest. The aim of this review is to analyze the …
Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation
AE Teschendorff, A Jones, H Fiegl, A Sargent… - Genome medicine, 2012 - Springer
Background Recently, it has been proposed that epigenetic variation may contribute to the
risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic …
risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic …
DNA methylation in peripheral blood: a potential biomarker for cancer molecular epidemiology
Aberrant DNA methylation is associated with cancer development and progression. There
are several types of specimens from which DNA methylation pattern can be measured and …
are several types of specimens from which DNA methylation pattern can be measured and …