[HTML][HTML] Targeting integrin pathways: mechanisms and advances in therapy
X Pang, X He, Z Qiu, H Zhang, R Xie, Z Liu… - … and Targeted Therapy, 2023 - nature.com
Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …
Focal adhesion dynamics in cellular function and disease
YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
[HTML][HTML] The extracellular matrix: its composition, function, remodeling, and role in tumorigenesis
The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease
SH Waddell, Y Yao, P Olaizola, A Walker… - Science translational …, 2023 - science.org
The formation of multiple cysts in the liver occurs in a number of isolated monogenic
diseases or multisystemic syndromes, during which bile ducts develop into fluid-filled biliary …
diseases or multisystemic syndromes, during which bile ducts develop into fluid-filled biliary …
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens
Q Mo, MFA Kulyar, C Quan, Y Ding, Y Zhang… - Journal of Hazardous …, 2023 - Elsevier
Pesticide thiram is widely used in agriculture and has been demonstrated to cause tibial
dyschondroplasia (TD) in birds. However, the underlying mechanism remains unclear. This …
dyschondroplasia (TD) in birds. However, the underlying mechanism remains unclear. This …
Advances in surface modifications of the silicone breast implant and impact on its biocompatibility and biointegration
Silicone breast implants are commonly used for cosmetic and oncologic surgical indications
owing to their inertness and being nontoxic. However, complications including capsular …
owing to their inertness and being nontoxic. However, complications including capsular …
[HTML][HTML] The multiple roles of periostin in non-neoplastic disease
L Yang, T Guo, Y Chen, K Bian - Cells, 2022 - mdpi.com
Periostin, identified as a matricellular protein and an ECM protein, plays a central role in non-
neoplastic diseases. Periostin and its variants have been considered to be normally …
neoplastic diseases. Periostin and its variants have been considered to be normally …
Calcium signaling in polycystic kidney disease-cell death and survival
KM Márquez-Nogueras, V Vuchkovska, IY Kuo - Cell Calcium, 2023 - Elsevier
Polycystic kidney disease is typified by cysts in the kidney and extra-renal manifestations
including hypertension and heart failure. The main genetic underpinning this disease are …
including hypertension and heart failure. The main genetic underpinning this disease are …
Whole transcriptome analysis provides new insight on immune response mechanism of golden pompano (Trachinotus ovatus) to Amyloodinium ocellatum infestation
J Niu, M Sun, Z Li, Z Wang, M Kong, Y Wang, J Song… - Aquaculture, 2022 - Elsevier
Ectoparasitic dinoflagellate Amyloodinium ocellatum (AO) is one of the most pathogenic
protozoan parasites, causing amyloodiniosis in temperate and tropical marine fish. Golden …
protozoan parasites, causing amyloodiniosis in temperate and tropical marine fish. Golden …
[HTML][HTML] Periostin augments vascular smooth muscle cell calcification via β-catenin signaling
I Alesutan, LA Henze, B Boehme, TTD Luong, D Zickler… - Biomolecules, 2022 - mdpi.com
Medial vascular calcification is common in chronic kidney disease (CKD) and is closely
linked to hyperphosphatemia. Vascular smooth muscle cells (VSMCs) can take up pro …
linked to hyperphosphatemia. Vascular smooth muscle cells (VSMCs) can take up pro …