Role of reactive oxygen species in myelodysplastic syndromes
Q Jing, C Zhou, J Zhang, P Zhang, Y Wu, J Zhou… - Cellular & Molecular …, 2024 - Springer
Reactive oxygen species (ROS) serve as typical metabolic byproducts of aerobic life and
play a pivotal role in redox reactions and signal transduction pathways. Contingent upon …
play a pivotal role in redox reactions and signal transduction pathways. Contingent upon …
Ex vivo anti-leukemic effect of exosome-like grapefruit-derived nanovesicles from organic farming—the potential role of ascorbic acid
G Castelli, M Logozzi, D Mizzoni, R Di Raimo… - International journal of …, 2023 - mdpi.com
Citrus fruits are a natural source of ascorbic acid, and exosome-like nanovesicles obtained
from these fruits contain measurable levels of ascorbic acid. We tested the ability of …
from these fruits contain measurable levels of ascorbic acid. We tested the ability of …
Targeting chemoresistance and mitochondria-dependent metabolic reprogramming in acute myeloid leukemia
Chemoresistance often complicates the management of cancer, as noted in the instance of
acute myeloid leukemia (AML). Mitochondrial function is considered important for the …
acute myeloid leukemia (AML). Mitochondrial function is considered important for the …
Vitamin C and D supplementation in acute myeloid leukemia
PL Mouchel, E Bérard, S Tavitian, N Gadaud… - Blood …, 2023 - ashpublications.org
Recent studies have highlighted the role of vitamin C and D in acute myeloid leukemia
(AML). In 2018, we changed our practices to add both vitamins to the supportive care for all …
(AML). In 2018, we changed our practices to add both vitamins to the supportive care for all …
Ascorbate Uptake and Retention by Breast Cancer Cell Lines and the Intracellular Distribution of Sodium-Dependent Vitamin C Transporter 2
C Praditi, SM Bozonet, GU Dachs, MCM Vissers - Antioxidants, 2023 - mdpi.com
Ascorbate plays a vital role as a co-factor for a superfamily of enzymes, the 2-oxoglutarate
dependent dioxygenases (2-OGDDs), which govern numerous pathways in cancer …
dependent dioxygenases (2-OGDDs), which govern numerous pathways in cancer …
Targeted Metabolomics Highlights Dramatic Antioxidant Depletion, Increased Oxidative/Nitrosative Stress and Altered Purine and Pyrimidine Concentrations in Serum …
R Mangione, C Giallongo, A Duminuco, E La Spina… - Antioxidants, 2024 - mdpi.com
To date, little is known concerning the circulating levels of biochemically relevant
metabolites (antioxidants, oxidative/nitrosative stress biomarkers, purines, and pyrimidines) …
metabolites (antioxidants, oxidative/nitrosative stress biomarkers, purines, and pyrimidines) …
Empowering γδ T‐cell functionality with vitamin C
D Kabelitz, L Cierna, C Juraske… - European Journal of …, 2024 - Wiley Online Library
Vitamin C (ascorbic acid) is a potent antioxidant and a cofactor for various enzymes
including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts …
including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts …