[HTML][HTML] Cellular and Molecular Determinants of Biologic Drugs Resistance and Therapeutic Failure in Inflammatory Bowel Disease
P Puca, I Capobianco, G Coppola… - International Journal of …, 2024 - mdpi.com
The advent of biologic drugs has revolutionized the treatment of Inflammatory Bowel
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Effects of DNA methylation and its application in inflammatory bowel disease
FA Akanyibah, Y Zhu, A Wan… - International …, 2024 - spandidos-publications.com
Inflammatory bowel disease (IBD) is marked by persistent inflammation, and its development
and progression are linked to environmental, genetic, immune system and gut microbial …
and progression are linked to environmental, genetic, immune system and gut microbial …
Baseline expression of immune gene modules in blood is associated with primary response to anti-TNF therapy in Crohn's disease patients
BYH Bai, M Reppell, N Smaoui… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background and Aims Anti-tumour necrosis factor [anti-TNF] therapy is widely used
for the treatment of inflammatory bowel disease, yet many patients are primary non …
for the treatment of inflammatory bowel disease, yet many patients are primary non …
Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts
A Gillespie, EM Walker, E Hannon, G McQueen… - medRxiv, 2023 - medrxiv.org
The second-generation antipsychotic clozapine is used as a medication for treatment-
resistant schizophrenia. It has previously been associated with epigenetic changes in pre …
resistant schizophrenia. It has previously been associated with epigenetic changes in pre …
Epigenetic Fingerprints in IBD: From Methylation Patterns to Clinical Implications
B Verstockt - Journal of Crohn's and Colitis, 2024 - academic.oup.com
Cracking the molecular code of inflammatory bowel diseases [IBD] to unravel disease
heterogeneity and ultimately improve patient outcomes has been at the forefront of …
heterogeneity and ultimately improve patient outcomes has been at the forefront of …
[PDF][PDF] Using genomic approaches to characterise the immune response to biologicals
S Lin - 2023 - ore.exeter.ac.uk
Biologic therapies are effective treatments for inflammatory bowel disease (IBD). Successful
treatment leads to reduced hospitalisation and surgeries, and an improvement in quality of …
treatment leads to reduced hospitalisation and surgeries, and an improvement in quality of …