Epigenetic clock: A promising biomarker and practical tool in aging
R Duan, Q Fu, Y Sun, Q Li - Ageing Research Reviews, 2022 - Elsevier
As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …
The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health
CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
[HTML][HTML] Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain
The diversity of cell types is a challenge for quantifying aging and its reversal. Here we
develop 'aging clocks' based on single-cell transcriptomics to characterize cell-type-specific …
develop 'aging clocks' based on single-cell transcriptomics to characterize cell-type-specific …
[HTML][HTML] Stress, diet, exercise: Common environmental factors and their impact on epigenetic age
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …
health conditions in clinical and research settings. They have enabled geroscientists to …
Late‐life exercise mitigates skeletal muscle epigenetic aging
There are functional benefits to exercise in muscle, even when performed late in life, but the
contributions of epigenetic factors to late‐life exercise adaptation are poorly defined. Using …
contributions of epigenetic factors to late‐life exercise adaptation are poorly defined. Using …
[HTML][HTML] A targeted epigenetic clock for the prediction of biological age
Epigenetic clocks were initially developed to track chronological age, but accumulating
evidence indicates that they can also predict biological age. They are usually based on the …
evidence indicates that they can also predict biological age. They are usually based on the …
[HTML][HTML] Insights into ageing rates comparison across tissues from recalibrating cerebellum DNA methylation clock
DNA methylation (DNAm)-based age clocks have been studied extensively as a biomarker
of human ageing and a risk factor for age-related diseases. Despite different tissues having …
of human ageing and a risk factor for age-related diseases. Despite different tissues having …
[HTML][HTML] Epigenetic age acceleration mediates the relationship between neighborhood deprivation and pain severity in adults with or at risk for knee osteoarthritis pain
An estimated 250 million people worldwide suffer from knee osteoarthritis (KOA), with older
adults having greater risk. Like other age-related diseases, residents of high-deprivation …
adults having greater risk. Like other age-related diseases, residents of high-deprivation …
[HTML][HTML] Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases
M Farrokhi, F Taheri, E Karami, R Khorram… - Kindle, 2023 - preferpub.org
The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …
are complex and interconnected. Environmental factors encompass external influences like …
Epigenetic clocks provide clues to the mystery of uterine ageing
PI Deryabin, AV Borodkina - Human Reproduction Update, 2023 - academic.oup.com
BACKGROUND Rising maternal ages and age-related fertility decline are a global
challenge for modern reproductive medicine. Clinicians and researchers pay specific …
challenge for modern reproductive medicine. Clinicians and researchers pay specific …