Cancer immunotherapy fights against cancer by modulating the immune response and is
delivering encouraging results in clinical treatments. However, it is challenging to achieve …

Background Primary central nervous system lymphoma (PCNSL) is a rare lymphoma of the
central nervous system, usually of diffuse large B cell phenotype. Stereotactic biopsy …

T cells expressing anti-CD19 chimeric antigen receptors (CARs) demonstrate impressive
efficacy in the treatment of systemic B cell malignancies, including B cell lymphoma …

Image‐guided core needle biopsies (IG‐CNB) represent a minimally invasive approach for
obtaining tissue in patients with lymphadenopathy and suspected lymphoma. Despite their …

Introduction Our previous studies have demonstrated that tumor-infiltrating lymphocytes
(TILs), including normal B cells, T cells, and natural killer (NK) cells, in diffuse large B-cell …

A rare tumor, primary central nervous system lymphoma can affect immunocompetent and
immunocompromised patients. While sensitive to radiotherapy or chemotherapy crossing …

Background Cancer is a mosaic of tumor cell subpopulations, where only a minority is
responsible for disease recurrence and cancer invasiveness. We focused on one of the most …

Objective In recent decades, frame-based (FBB) and frame-less stereotactic brain biopsy
(FLB) have played a crucial role in defining the diagnosis and management of expanding …

Different tumors can be encountered in the paraventricular regions, and whereas their deep
location often make them difficult to access surgically, they may be amenable to …

Background To assess the sensitivity, specificity and turnaround time of flow cytometric
analysis on brain biopsies compared to histology plus immunohistochemistry analysis in …