Stress, epigenetics and depression: a systematic review

C Park, JD Rosenblat, E Brietzke, Z Pan, Y Lee… - Neuroscience & …, 2019 - Elsevier
Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches

SH Parade, L Huffhines, TE Daniels, LR Stroud… - Translational …, 2021 - nature.com
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review

CAM Cecil, Y Zhang, T Nolte - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

Epigenetics in depression and gut-brain axis: A molecular crosstalk

N Begum, A Mandhare, KP Tryphena… - Frontiers in Aging …, 2022 - frontiersin.org
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …

Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

MA Schiele, K Domschke - Genes, Brain and Behavior, 2018 - Wiley Online Library
The pathogenesis of anxiety disorders is multifactorial, involving complex interactions
between biological factors, environmental influences and psychological mechanisms …

[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment

KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …

[HTML][HTML] The applied implications of epigenetics in anxiety, affective and stress-related disorders-A review and synthesis on psychosocial stress, psychotherapy and …

MA Schiele, MG Gottschalk, K Domschke - Clinical psychology review, 2020 - Elsevier
Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

BJ Ellis, AJ Horn, CS Carter, MH van IJzendoorn… - Clinical Psychology …, 2021 - Elsevier
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

The caring continuum: Evolved hormonal and proximal mechanisms explain prosocial and antisocial extremes

AA Marsh - Annual Review of Psychology, 2019 - annualreviews.org
Implicit in the long-standing disagreements about whether humans' fundamental nature is
predominantly caring or callous is an assumption of uniformity. This article reviews evidence …

A review of DNA methylation in depression

D Chen, L Meng, F Pei, Y Zheng, J Leng - Journal of Clinical Neuroscience, 2017 - Elsevier
As one of the most common psychiatric disorders, depression has been a major public
health problem. Growing evidence suggests that epigenetic modification is essential in …