Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Abstract Purpose of Review Developmental toxicity assessments often focus on structural
outcomes and overlook subtle metabolic differences which occur during the early embryonic …

The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during
which the maternal environment is converted to an environment of embryonic-driven …

Early embryonic development is driven exclusively by maternal gene products deposited
into the oocyte. Although critical in establishing early developmental programs, maternal …

Intracellular targeting of mRNAs has long been recognized as a means to produce proteins
locally, but has only recently emerged as a prevalent mechanism used by a wide variety of …

Quantifying cell behaviors in animal early embryogenesis remains a challenging issue
requiring in toto imaging and automated image analysis. We designed a framework for …

The production of fertile eggs with the capacity to develop into larvae and subsequently into
marketable fish is centrally important to the aquaculture industry. This entails not only the …

Maternally deposited mRNAs direct early development before the initiation of zygotic
transcription during mid-blastula transition (MBT). To study mechanisms regulating this …

The capability to conditionally inactivate gene function is essential for understanding the
molecular basis of development. In gene and mRNA targeting approaches, protein products …

Vertebrate development begins with precise molecular, cellular, and morphogenetic controls
to establish the basic body plan of the embryo. In zebrafish, these tightly regulated …