[HTML][HTML] Abdominal aortic aneurysm: roles of inflammatory cells
Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
[HTML][HTML] Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
Mouse models for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Deficiency of ITGAM attenuates experimental abdominal aortic aneurysm in mice
M Zhou, X Wang, Y Shi, Y Ding, X Li, T Xie… - Journal of the …, 2021 - Am Heart Assoc
Background Integrin αM (CD11b), which is encoded by the Integrin Subunit Alpha M
(ITGAM) gene, is not only a surface marker of monocytes but also an essential adhesion …
(ITGAM) gene, is not only a surface marker of monocytes but also an essential adhesion …
[HTML][HTML] High-dimensional immune profiling by mass cytometry revealed the circulating immune cell landscape in patients with intracranial aneurysm
P Ge, C Liu, L Chan, Y Pang, H Li, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Increasing evidence supports a critical role of chronic inflammation in
intracranial aneurysm (IA). Understanding how the immunological alterations in IA provides …
intracranial aneurysm (IA). Understanding how the immunological alterations in IA provides …
Neutrophil elastase inhibition by sivelestat (ONO-5046) attenuates AngII-induced abdominal aortic aneurysms in apolipoprotein E-deficient mice
Y Hada, HA Uchida, S Okamoto, N Otaka… - American Journal of …, 2024 - academic.oup.com
BACKGROUND Abdominal aortic aneurysm (AAA) is an arterial disease characterized by
dilatation of the aortic wall. It has been suggested that neutrophil counts and neutrophil …
dilatation of the aortic wall. It has been suggested that neutrophil counts and neutrophil …
Fluoroquinolones increase susceptibility to aortic aneurysm and aortic dissection: Molecular mechanism and clinical evidence
X Xuan, Y Li, G Cao, R Zhang, J Hu, H Jin… - Vascular …, 2023 - journals.sagepub.com
Aortic aneurysm (AA) and aortic dissection (AD) are prevalent severe cardiovascular
diseases that result in catastrophic complications and unexpected deaths. Owing to the lack …
diseases that result in catastrophic complications and unexpected deaths. Owing to the lack …
[HTML][HTML] Profiles of immune infiltration in abdominal aortic aneurysm and their associated marker genes: a gene expression-based study
T Li, T Wang, X Zhao - Brazilian Journal of Medical and Biological …, 2021 - SciELO Brasil
Immune-mediated inflammation plays a key role in the pathology of abdominal aortic
aneurysm (AAA). We aimed to use a computational approach to profile the immune …
aneurysm (AAA). We aimed to use a computational approach to profile the immune …
CD248+ CD8+ T lymphocytes suppress pathological vascular remodeling in human thoracic aortic aneurysms
X Hu, T Wu, C Wang, J Li… - Experimental Biology and …, 2021 - journals.sagepub.com
Aortic aneurysms are characterized by vascular inflammation, neovascularization, and
extracellular matrix destruction of the aortic wall. Although experimental studies indicate a …
extracellular matrix destruction of the aortic wall. Although experimental studies indicate a …
Depletion of CD11c+ cell attenuates progression of abdominal aortic aneurysm
K Okuno, S Cicalese, S Eguchi - Clinical Science, 2020 - portlandpress.com
Chronic inflammation of the arterial wall has been implicated in the development of
abdominal aortic aneurysm (AAA). However, the detailed molecular mechanism (s) by which …
abdominal aortic aneurysm (AAA). However, the detailed molecular mechanism (s) by which …