Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

Volatile organic compounds of lung cancer and possible biochemical pathways

M Hakim, YY Broza, O Barash, N Peled… - Chemical …, 2012 - ACS Publications
Lung cancer (LC) is the leading cause of cancer mortality, with more than 1 million deaths
worldwide every year. 1, 2 There are two major forms of LC disease: nonsmall cell LC …

Assessment, origin, and implementation of breath volatile cancer markers

H Haick, YY Broza, P Mochalski, V Ruzsanyi… - Chemical Society …, 2014 - pubs.rsc.org
A new non-invasive and potentially inexpensive frontier in the diagnosis of cancer relies on
the detection of volatile organic compounds (VOCs) in exhaled breath samples. Breath can …

Hallmarks of the ageing lung

S Meiners, O Eickelberg… - European Respiratory …, 2015 - Eur Respiratory Soc
Ageing is the main risk factor for major non-communicable chronic lung diseases, including
chronic obstructive pulmonary disease, most forms of lung cancer and idiopathic pulmonary …

[HTML][HTML] Pulmonary-intestinal cross-talk in mucosal inflammatory disease

S Keely, NJ Talley, PM Hansbro - Mucosal immunology, 2012 - Elsevier
Chronic obstructive pulmonary disease (COPD) and inflammatory bowel diseases (IBDs)
are chronic inflammatory diseases of mucosal tissues that affect the respiratory and …

Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis

IV Yang, BS Pedersen, E Rabinovich… - American journal of …, 2014 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is an untreatable and often fatal lung disease
that is increasing in prevalence and is caused by complex interactions between genetic and …

Is chronic obstructive pulmonary disease an accelerated aging disease?

W MacNee - Annals of the American Thoracic Society, 2016 - atsjournals.org
Aging is one of the most important risk factors for most chronic diseases. The worldwide
increase in life expectancy has been accompanied by an increase in the prevalence of age …

Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study

Z Zhu, Y Li, RJ Freishtat, JC Celedón… - Nature …, 2023 - nature.com
Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …

A systematic review of smoking-related epigenetic alterations

G Kaur, R Begum, S Thota, S Batra - Archives of Toxicology, 2019 - Springer
The aim of this study is to provide a systematic review of the known epigenetic alterations
caused by cigarette smoke; establish an evidence-based perspective of their clinical value …

Lung–gut cross‐talk: evidence, mechanisms and implications for the mucosal inflammatory diseases

MK Tulic, T Piche, V Verhasselt - Clinical & Experimental …, 2016 - Wiley Online Library
The mucosal immune system (including airway, intestinal, oral and cervical epithelium) is an
integrated network of tissues, cells and effector molecules that protect the host from …