While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

This review describes stress-related biological mechanisms linking interpersonal racism to
life course health trajectories among African Americans. Interpersonal racism, a form of …

Aging of organisms begins from a single cell at the molecular level. It includes changes
related to telomere shortening, cell senescence and epigenetic modifications. These …

Background Childhood maltreatment is closely related to normal cognitive development and
ensuing adverse mental health outcomes and cognitive dysfunction. Our current …

In recent years, striking new evidence has demonstrated non-genetic inheritance of
acquired traits associated with parental environmental exposures. In particular, this …

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Human pluripotent stem cells (hPSCs) are being increasingly utilized worldwide in
investigating human development, and modeling and discovering therapies for a wide range …

DNA methylation, a central component of the epigenetic network is altered in response to
nutritional influences. In one-carbon cycle, folate acts as a one-carbon carrier and vitamin …

Adverse childhood experiences (ACEs) increase risk for depression at subsequent ages
and have been linked to accelerated biological aging. We hypothesize that accelerated …

Polyploidy plays an important role in plant diversification and speciation. The ploidy level of
plants is associated with morphological and biochemical characteristics, and its modification …