Aspergillus fumigatus morphology and dynamic host interactions
FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
Regulation and role of fungal secondary metabolites
J Macheleidt, DJ Mattern, J Fischer… - Annual review of …, 2016 - annualreviews.org
Fungi have the capability to produce a tremendous number of so-called secondary
metabolites, which possess a multitude of functions, eg, communication signals during …
metabolites, which possess a multitude of functions, eg, communication signals during …
Metals in fungal virulence
F Gerwien, V Skrahina, L Kasper… - FEMS microbiology …, 2018 - academic.oup.com
Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …
[HTML][HTML] Fungal iron homeostasis with a focus on Aspergillus fumigatus
M Misslinger, P Hortschansky, AA Brakhage… - Biochimica et Biophysica …, 2021 - Elsevier
To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …
The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence
V Valiante, J Macheleidt, M Föge… - Frontiers in …, 2015 - frontiersin.org
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …
Impacts of soil abiotic attributes on Fusarium wilt, focusing on bananas
Production of many crops, including bananas, is threatened worldwide by the spread of
pathogenic strains of Fusarium oxysporum, the causal agent of Fusarium wilt. Severity of the …
pathogenic strains of Fusarium oxysporum, the causal agent of Fusarium wilt. Severity of the …
Studies of Pseudomonas aeruginosa mutants indicate pyoverdine as the central factor in inhibition of Aspergillus fumigatus biofilm
G Sass, H Nazik, J Penner, H Shah… - Journal of …, 2018 - Am Soc Microbiol
Pseudomonas aeruginosa and Aspergillus fumigatus are common opportunistic bacterial
and fungal pathogens, respectively. They often coexist in airways of immunocompromised …
and fungal pathogens, respectively. They often coexist in airways of immunocompromised …
HapX-mediated H2B deub1 and SreA-mediated H2A. Z deposition coordinate in fungal iron resistance
Plant pathogens are challenged by host-derived iron starvation or excess during infection,
but the mechanism through which pathogens counteract iron stress is unclear. Here, we …
but the mechanism through which pathogens counteract iron stress is unclear. Here, we …
Inhibition of histone acetyltransferase GCN5 by a transcription factor FgPacC controls fungal adaption to host-derived iron stress
Q Gu, Y Wang, X Zhao, B Yuan, M Zhang… - Nucleic Acids …, 2022 - academic.oup.com
Poaceae plants can locally accumulate iron to suppress pathogen infection. It remains
unknown how pathogens overcome host-derived iron stress during their successful …
unknown how pathogens overcome host-derived iron stress during their successful …
Sterol biosynthesis and azole tolerance is governed by the opposing actions of SrbA and the CCAAT binding complex
F Gsaller, P Hortschansky, T Furukawa, PD Carr… - PLoS …, 2016 - journals.plos.org
Azole drugs selectively target fungal sterol biosynthesis and are critical to our antifungal
therapeutic arsenal. However, resistance to this class of drugs, particularly in the major …
therapeutic arsenal. However, resistance to this class of drugs, particularly in the major …