Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives
FF Kreiner, JM Kraaijenhof, M von Herrath… - Expert Review of …, 2022 - Taylor & Francis
Introduction Diabetes, chronic kidney disease (CKD) and cardiovascular disease (CVD) are
cardiometabolic diseases that remain amongst the leading causes of morbidity and …
cardiometabolic diseases that remain amongst the leading causes of morbidity and …
Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE−/− mice
Z Wang, J Guo, X Han, M Xue, W Wang, L Mi, Y Sheng… - Cell & bioscience, 2019 - Springer
Background The protective effect of metformin (MET) on abdominal aortic aneurysm (AAA)
has been reported. However, the related mechanism is still poor understood. In this study …
has been reported. However, the related mechanism is still poor understood. In this study …
Neutrophils as regulators and biomarkers of cardiovascular inflammation in the context of abdominal aortic aneurysms
J Klopf, C Brostjan, C Neumayer, W Eilenberg - Biomedicines, 2021 - mdpi.com
Neutrophils represent up to 70% of circulating leukocytes in healthy humans and combat
infection mostly by phagocytosis, degranulation and NETosis. It has been reported that …
infection mostly by phagocytosis, degranulation and NETosis. It has been reported that …
Proteomics analysis of genetic liability of abdominal aortic aneurysm identifies plasma neogenin and kit Ligand: the ARIC Study
BT Steffen, JS Pankow, FL Norby… - … , and vascular biology, 2023 - Am Heart Assoc
Background: Genome-wide association studies have reported 23 gene loci related to
abdominal aortic aneurysm (AAA)—a potentially lethal condition characterized by a …
abdominal aortic aneurysm (AAA)—a potentially lethal condition characterized by a …
Global research status analysis of the association between aortic aneurysm and inflammation: a bibliometric analysis from 1999 to 2023
Q Wang, G Chen, Z Qi, Y Zeng, L Tan… - Frontiers in …, 2023 - frontiersin.org
Background Aortic aneurysm is a chronic arterial disease that can lead to aortic rupture,
causing severe complications and life-threatening risks for patients, and it is one of the …
causing severe complications and life-threatening risks for patients, and it is one of the …
[HTML][HTML] Diagnostic and predictive values of circulating tetrahydrobiopterin levels as a novel biomarker in patients with thoracic and abdominal aortic aneurysms
Y Zhang, KL Siu, Q Li, K Howard-Quijano, J Scovotti… - Redox Biology, 2022 - Elsevier
We have previously shown that circulating levels of tetrahydrobiopterin (H 4 B) function as a
robust biomarker for aortic aneurysms in several independent animal models. In the present …
robust biomarker for aortic aneurysms in several independent animal models. In the present …
Assessing the causal relationship between circulating immune cells and abdominal aortic aneurysm by bi-directional Mendelian randomization analysis
W Ruan, X Zhou, T Wang, H Liu, G Zhang, J Sun… - Scientific Reports, 2024 - nature.com
Although there is an association between abdominal aortic aneurysm (AAA) and circulating
immune cell phenotypes, the exact causal relationship remains unclear. This study aimed to …
immune cell phenotypes, the exact causal relationship remains unclear. This study aimed to …
Blood biomarker panel recommended for personalized prediction, prognosis, and prevention of complications associated with abdominal aortic aneurysm
J Molacek, V Treska, J Zeithaml, I Hollan, O Topolcan… - EPMA Journal, 2019 - Springer
The aim of the study was to evaluate the ability of following biomarkers as diagnostic tools
and risk predictors of AAA: C-reactive protein, interleukin-6, pentraxin-3, galectin-3 …
and risk predictors of AAA: C-reactive protein, interleukin-6, pentraxin-3, galectin-3 …
Smoking, hypertension, and GG genotype of the IL-6 rs1800796 polymorphism are independent risk factors for abdominal aortic aneurysm in Han population
Y Zhang, G Xu, P Wang - Pharmacogenomics and Personalized …, 2021 - Taylor & Francis
Background Recent researches have investigated the link between the rs1800796
polymorphism (− 572G/C) in the interleukin-6 (IL-6) gene and the risk of abdominal aortic …
polymorphism (− 572G/C) in the interleukin-6 (IL-6) gene and the risk of abdominal aortic …