Intermediate DNA methylation is a conserved signature of genome regulation
The role of intermediate methylation states in DNA is unclear. Here, to comprehensively
identify regions of intermediate methylation and their quantitative relationship with gene …
identify regions of intermediate methylation and their quantitative relationship with gene …
Fetal lung and placental methylation is associated with in utero nicotine exposure
D Chhabra, S Sharma, AT Kho, R Gaedigk… - Epigenetics, 2014 - Taylor & Francis
In utero smoke exposure has been shown to have detrimental effects on lung function and to
be associated with persistent wheezing and asthma in children. One potential mechanism of …
be associated with persistent wheezing and asthma in children. One potential mechanism of …
Drought stress memory in rice guard cells: Proteome changes and genomic stability of DNA
Drought is one of the major threats for crop plants among them rice, worldwide. The effects
of drought vary depending on the plant growth phase and the occurrence of a previous …
of drought vary depending on the plant growth phase and the occurrence of a previous …
[HTML][HTML] Pup1 QTL regulates gene expression through epigenetic modification of DNA under phosphate starvation stress in rice
Cytosine methylation, epigenetic DNA modification, is well known to regulate gene
expression. Among the epigenetic modifications, 5-methylcytosine (5-mC) has been one of …
expression. Among the epigenetic modifications, 5-methylcytosine (5-mC) has been one of …
[HTML][HTML] Epigenetics in the hematologic malignancies
CY Fong, J Morison, MA Dawson - Haematologica, 2014 - ncbi.nlm.nih.gov
A wealth of genomic and epigenomic data has identified abnormal regulation of epigenetic
processes as a prominent theme in hematologic malignancies. Recurrent somatic …
processes as a prominent theme in hematologic malignancies. Recurrent somatic …
[HTML][HTML] Epigenetics and autoimmune diseases
P Quintero-Ronderos, G Montoya-Ortiz - Autoimmune diseases, 2012 - hindawi.com
Epigenetics is defined as the study of all inheritable and potentially reversible changes in
genome function that do not alter the nucleotide sequence within the DNA. Epigenetic …
genome function that do not alter the nucleotide sequence within the DNA. Epigenetic …
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia
M Almamun, BT Levinson, AC Van Swaay… - Epigenetics, 2015 - Taylor & Francis
Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children
under the age of 15. In addition to genetic aberrations, epigenetic modifications such as …
under the age of 15. In addition to genetic aberrations, epigenetic modifications such as …
Epigenetics and the developmental origins of lung disease
LA Joss-Moore, RH Lane, KH Albertine - The Lung, 2014 - Elsevier
Environmental disruptions during the course of lung development produce long-term
changes in lung structure and function that predispose towards adult lung disease, a …
changes in lung structure and function that predispose towards adult lung disease, a …
Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes
MG Dozmorov - Epigenetics, 2015 - Taylor & Francis
Although age-associated gene expression and methylation changes have been reported
throughout the literature, the unifying epigenomic principles of aging remain poorly …
throughout the literature, the unifying epigenomic principles of aging remain poorly …
Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation
Age is a key risk factor for breast cancer and epigenetic alterations may contribute to age-
related increases in breast cancer risk, though the relation of age-related methylation in …
related increases in breast cancer risk, though the relation of age-related methylation in …