Schizophrenia is a devastating mental illness with a strong genetic component that is the
subject of extensive research. Despite the high heritability, it is well recognized that non …

Advances in genomics are opening new windows into the biology of schizophrenia. Though
common variants individually have small effects on disease risk, GWAS provide a powerful …

Background Diagnosis and treatment of complex diseases such as Neurodevelopmental
Disorders (NDDs) can be resolved through the identification of biomarkers. Metallomics …

Schizophrenia (SZ) is a highly heterogeneous disorder in both its symptoms and risk factors.
One of the most prevalent genetic risk factors for SZ is the hemizygous microdeletion at …

Changes in the actin cytoskeleton are a primary mechanism mediating the morphological
and functional plasticity that underlies learning and memory. The synaptic Ras homologous …

Schizophrenia is a severe disorder characterized by positive, negative and cognitive
symptoms, which are still not fully understood. The development of efficient antipsychotics …

Schizophrenia (SZ) is a complex neuropsychiatric disorder, affecting 1% of the world
population. Long-standing clinical observations and molecular data have pointed to a …

Schizophrenia (SZ) is a severe psychotic disorder that is highly heritable and common in the
general population. The genetic heterogeneity of SZ is substantial, with contributions from …

Abstract A missense mutation (A391T) in SLC39A8 is strongly associated with
schizophrenia in genomic studies, though the molecular connection to the brain is unknown …

Abstract Purpose of Review We review the ways in which stem cells are used in psychiatric
disease research, including the related advances in gene editing and directed cell …