Chromosomal microarray analysis as First-Tier genetic test for schizophrenia
CH Chen, MC Cheng, TM Hu, LY Ping - Frontiers in Genetics, 2021 - frontiersin.org
Schizophrenia is a chronic, devastating mental disorder with complex genetic components.
Given the advancements in the molecular genetic research of schizophrenia in recent years …
Given the advancements in the molecular genetic research of schizophrenia in recent years …
Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia
WA Akingbuwa, AR Hammerschlag, M Bartels… - Molecular …, 2022 - nature.com
Both common and rare genetic variants (minor allele frequency> 1% and< 0.1%
respectively) have been implicated in the aetiology of schizophrenia. In this study, we …
respectively) have been implicated in the aetiology of schizophrenia. In this study, we …
Chemoinformatic studies on some inhibitors of dopamine transporter and the receptor targeting schizophrenia for developing novel antipsychotic agents
Chemoinformatic studies were carried on some inhibitors of dopamine transporter to
develop a predictive and robust QSAR model and also to elucidate binding mode and …
develop a predictive and robust QSAR model and also to elucidate binding mode and …
[HTML][HTML] Polygenic risk score for schizophrenia was not associated with glycemic level (HbA1c) in patients with non-affective psychosis: Genetic Risk and Outcome of …
TD Habtewold, MA Islam, EJ Liemburg… - Journal of …, 2020 - Elsevier
Abstract Introduction Type 2 diabetes (T2D) is a common comorbidity in patients with
schizophrenia (SCZ). The underlying pathophysiologic mechanisms are yet to be fully …
schizophrenia (SCZ). The underlying pathophysiologic mechanisms are yet to be fully …
A Missense Variant in CASKIN1's Proline-Rich Region Segregates with Psychosis in a Three-Generation Family
MH Wahbeh, X Peng, S Bacharaki, A Hatzimanolis… - Genes, 2023 - mdpi.com
The polygenic nature of schizophrenia (SCZ) implicates many variants in disease
development. Rare variants of high penetrance have been shown to contribute to the …
development. Rare variants of high penetrance have been shown to contribute to the …
Investigating temporal and prosodic markers in clinical high‐risk for psychosis participants using automated acoustic analysis
B Bianciardi, R Gajwani, J Gross… - Early intervention in …, 2023 - Wiley Online Library
Aim Language disturbances are a candidate biomarker for the early detection of psychosis.
Temporal and prosodic abnormalities have been observed in schizophrenia patients, while …
Temporal and prosodic abnormalities have been observed in schizophrenia patients, while …
Illusions, delusions, and your backwards bayesian brain: a biased visual perspective
RT Born, GM Bencomo - Brain Behavior and Evolution, 2021 - karger.com
The retinal image is insufficient for determining what is “out there,” because many different
real-world geometries could produce any given retinal image. Thus, the visual system must …
real-world geometries could produce any given retinal image. Thus, the visual system must …
Development of novel antipsychotic agents by inhibiting dopamine transporter–in silico approach
V Đorđević, S Pešić, J Živković, GM Nikolić… - New Journal of …, 2022 - pubs.rsc.org
Dopamine transporter inhibition is deemed a promising approach to treating schizophrenia.
This research paper outlines various QSAR models for molecules acting as dopamine …
This research paper outlines various QSAR models for molecules acting as dopamine …
[HTML][HTML] Plasma miRNAs as potential biomarkers for schizophrenia in a Jordanian cohort
Background Schizophrenia (SZ), a complex and chronic neuropsychiatric disorder affecting
approximately 1% of the general population, presents diagnostic challenges due to the …
approximately 1% of the general population, presents diagnostic challenges due to the …
Transcriptomics and machine learning to advance schizophrenia genetics: a case-control study using post-mortem brain data
B Qi, S Boscenco, J Ramamurthy… - Computer Methods and …, 2022 - Elsevier
Abstract Background and Objective Alterations of the expression of a variety of genes have
been reported in patients with schizophrenia (SCZ). Moreover, machine learning (ML) …
been reported in patients with schizophrenia (SCZ). Moreover, machine learning (ML) …