LINE-1 methylation is positively associated with healthier lifestyle but inversely related to body fat mass in healthy young individuals

JL Marques-Rocha, FI Milagro, ML Mansego… - Epigenetics, 2016 - Taylor & Francis
With the goal of investigating if epigenetic biomarkers from white blood cells (WBC) are
associated with dietary, anthropometric, metabolic, inflammatory and oxidative stress …

[HTML][HTML] Epigenética y obesidad

P Casanello, BJ Krause, JA Castro-Rodríguez… - Revista chilena de …, 2016 - Elsevier
Current evidence supports the notion that exposure to various environmental conditions in
early life may induce permanent changes in the epigenome that persist throughout the life …

Mediterranean diet and particulate matter exposure are associated with LINE-1 methylation: results from a cross-sectional study in women

M Barchitta, A Maugeri, A Quattrocchi, G Barone… - Frontiers in …, 2018 - frontiersin.org
Emerging evidence suggests that air pollution increases the risk of cardiovascular disease
(CVD) and metabolic disorders, adding to the global burden of disease attributable to …

Novel associations between blood DNA methylation and body mass index in middle-aged and older adults

YM Geurts, PA Dugue, JE Joo, E Makalic… - International journal of …, 2018 - nature.com
Results: Cross-sectional analysis identified 310 CpGs associated with BMI with P< 1.0× 10−
7, 225 of which had not been reported previously. Of these 225 novel associations, 172 …

Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status

K King, S Murphy, C Hoyo - J Epidemiol Community Health, 2015 - jech.bmj.com
Background Children born to parents with lower income and education are at risk for obesity
and later-life risk of common chronic diseases, and epigenetics has been hypothesised to …

Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma

A Fröhlich, J Sirokay, S Fietz, TJ Vogt, J Dietrich… - …, 2020 - thelancet.com
Background The co-receptor lymphocyte-activation gene-3 (LAG3, LAG-3, CD223) is a
potential target for immune checkpoint inhibition immunotherapies. However, little is known …

[HTML][HTML] Counteracting aged DNA methylation states to combat ageing and age-related diseases

A Reale, S Tagliatesta, G Zardo, M Zampieri - Mechanisms of Ageing and …, 2022 - Elsevier
DNA methylation (DNAm) overwrites information about multiple extrinsic factors on the
genome. Age is one of these factors. Age causes characteristic DNAm changes that are …

Methylation levels at imprinting control regions are not altered with ovulation induction or in vitro fertilization in a birth cohort

RC Rancourt, HR Harris, KB Michels - Human reproduction, 2012 - academic.oup.com
STUDY QUESTION Do fertility treatments, including ovulation induction (OI), alter epigenetic
mechanisms such as DNA methylation at imprinted loci? SUMMARY ANSWER We …

Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments

A Rossnerova, E Tulupova, N Tabashidze… - Mutation Research …, 2013 - Elsevier
Gene expression levels are significantly regulated by DNA methylation. Differences in gene
expression profiles in the populations from various locations with different environmental …

White blood cell global methylation and IL-6 promoter methylation in association with diet and lifestyle risk factors in a cancer-free population

FF Zhang, RM Santella, M Wolff, MA Kappil… - Epigenetics, 2012 - Taylor & Francis
Altered levels of global DNA methylation and gene silencing through methylation of
promoter regions can impact cancer risk, but little is known about their environmental …