Epigenetic modifications associated with in utero exposure to endocrine disrupting chemicals BPA, DDT and Pb
Endocrine disrupting chemicals (EDCs) are xenobiotics which adversely modify the
hormone system. The endocrine system is most vulnerable to assaults by endocrine …
hormone system. The endocrine system is most vulnerable to assaults by endocrine …
Epigenetic variability in systemic lupus erythematosus: what we learned from genome-wide DNA methylation studies
M Teruel, AH Sawalha - Current rheumatology reports, 2017 - Springer
Purpose of Review DNA methylation has emerged as an important contributing factor in the
pathogenesis of systemic lupus erythematosus (SLE). Here, we describe the DNA …
pathogenesis of systemic lupus erythematosus (SLE). Here, we describe the DNA …
[HTML][HTML] Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
Background GrimAge acceleration (GAA), an epigenetic marker that represents physiologic
aging, is associated with atherosclerotic cardiovascular disease. However, the associations …
aging, is associated with atherosclerotic cardiovascular disease. However, the associations …
[HTML][HTML] Global methylation levels in peripheral blood leukocyte DNA by LUMA and breast cancer: a case–control study in Japanese women
A Kuchiba, M Iwasaki, H Ono, Y Kasuga… - British journal of …, 2014 - nature.com
Background: Global hypomethylation has been suggested to cause genomic instability and
lead to an increased risk of cancer. We examined the association between the global …
lead to an increased risk of cancer. We examined the association between the global …
[HTML][HTML] Do human endogenous retroviruses contribute to multiple sclerosis, and if so, how?
G Morris, M Maes, M Murdjeva, BK Puri - Molecular Neurobiology, 2019 - Springer
The gammaretroviral human endogenous retrovirus (HERV) families MRSV/HERV-W and
HERV-H (including the closely related HERV-Fc1) are associated with an increased risk of …
HERV-H (including the closely related HERV-Fc1) are associated with an increased risk of …
The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: a systematic review
Background New evidence suggests the potential involvement of epigenetic mechanisms in
type 2 diabetes (T2D) as a crucial interface between the effects of genetic predisposition and …
type 2 diabetes (T2D) as a crucial interface between the effects of genetic predisposition and …
Effects of lifestyle interventions on epigenetic signatures of liver fat: Central randomized controlled trial
A Yaskolka Meir, M Keller, L Müller… - Liver …, 2021 - Wiley Online Library
Abstract Background and Aims In the CENTRAL trial context, we found diverse liver fat
dynamics in response to different dietary interventions. Epigenetic mechanisms may …
dynamics in response to different dietary interventions. Epigenetic mechanisms may …
[HTML][HTML] Tobacco smoking is associated with methylation of genes related to coronary artery disease
RV Steenaard, S Ligthart, L Stolk, MJ Peters… - Clinical …, 2015 - Springer
Background Tobacco smoking, a risk factor for coronary artery disease (CAD), is known to
modify DNA methylation. We hypothesized that tobacco smoking modifies methylation of the …
modify DNA methylation. We hypothesized that tobacco smoking modifies methylation of the …
Epigenome-wide association in adipose tissue from the METSIM cohort
Most epigenome-wide association studies to date have been conducted in blood. However,
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …
[HTML][HTML] Prediction of chronological and biological age from laboratory data
Aging has pronounced effects on blood laboratory biomarkers used in the clinic. Prior
studies have largely investigated one biomarker or population at a time, limiting a …
studies have largely investigated one biomarker or population at a time, limiting a …