The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …

Abdominal aortic aneurysm (AAA) affects∼ 5% men aged over 65 years and is an important
cause of death in this population. Research into AAA pathogenesis has been fuelled by the …

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life threatening disease.
Many animal models have been developed to simulate the natural history of the disease or …

Background Abdominal aortic aneurysm (AAA) is a potentially life‐threatening disease that
is common in older individuals. Currently, therapeutic options are limited to surgical …

HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase inhibitors (statins) have been
suggested to attenuate abdominal aortic aneurysm (AAA) growth. However, the effects of …

Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence
is accumulating to support a central role for inflammation. Inflammatory responses are …

BACKGROUND: It is hypothesized that activation of extracellular signal-related kinase
(ERK) is critical in activating matrix metalloproteinases (MMPs) during abdominal aortic …

Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth
and rupture of aortic wall with a high death rate. Several studies have found that treatment …

OBJECTIVE: An ideal animal model of abdominal aortic aneurysm (AAA) is of great
importance for clarifying unknown complex mechanisms of the pathogenesis. We introduce …

Abstract Background Mesenchymal stem cells (MSCs) are known to be capable of
suppressing inflammatory responses. We previously reported that intra-abdominal …