Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of
immune tolerance and sustained production of autoantibodies. Multiple and profound T cell …

Even though the importance of epigenetics was first recognized in light of its role in tissue
development, an increasing amount of evidence has shown that it also plays an important …

The genome-wide association study is a free-hypothesis approach based on screening of
thousands or even millions of genetic variants distributed throughout the whole human …

Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with
heterogeneous presentation and complex aetiology where DNA methylation changes are …

By producing various cytokines, expanded DNT cells in inflamed tissues contribute to the
pathogenesis of a variety of autoimmune inflammatory diseases. However, it is unclear …

Background Psoriasis is an autoimmune/inflammatory disorder primarily affecting the skin.
Chronic joint inflammation triggers the diagnosis of psoriatic arthritis (PsA) in approximately …

Systemic lupus erythematosus (SLE) has a complex clinical picture, and a number of defects
in the immune system have been described in patients with the disease. Most organs can be …

The HCP5 RNA gene (NCBI ID: 10866) is located centromeric of the HLA-B gene and
between the MICA and MICB genes within the major histocompatibility complex (MHC) class …

Systemic lupus erythematosus (SLE or lupus) is a heterogeneous autoimmune disease
characterized by the involvement of multiple organs and the production of antinuclear …

The immune system constantly monitors the emergence of cancerous cells and eliminates
them. CD8+ cytotoxic T lymphocytes (CTLs), which kill tumor cells and provide antitumor …