Progress toward liquid biopsies in pediatric solid tumors

DA Weiser, DC West-Szymanski, E Fraint… - Cancer and Metastasis …, 2019 - Springer
Pediatric solid tumors have long been known to shed tumor cells, DNA, RNA, and proteins
into the blood. Recent technological advances have allowed for improved capture and …

Epigenetic regulation of neuroblastoma development

K Durinck, F Speleman - Cell and Tissue Research, 2018 - Springer
In recent years, technological advances have enabled a detailed landscaping of the
epigenome and the mechanisms of epigenetic regulation that drive normal cell function …

Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines

JL Harenza, MA Diamond, RN Adams, MM Song… - Scientific Data, 2017 - nature.com
Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic
drivers of the disease. While many of these cell lines have been previously characterized …

[HTML][HTML] Methylome-wide analysis of milk somatic cells upon subclinical mastitis in dairy cattle

D Giannuzzi, E Capra, V Bisutti, A Vanzin… - Journal of Dairy …, 2024 - Elsevier
Better understanding of the molecular mechanisms behind bovine mastitis is fundamental
for improving the management of this disease, which continues to be of major concern for …

Neuroblastoma, a paradigm for big data science in pediatric oncology

BM Salazar, EA Balczewski, CY Ung, S Zhu - International journal of …, 2016 - mdpi.com
Pediatric cancers rarely exhibit recurrent mutational events when compared to most adult
cancers. This poses a challenge in understanding how cancers initiate, progress, and …

[HTML][HTML] MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

J Fabian, D Opitz, K Althoff, M Lodrini, B Hero… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The systemic and resistant nature of metastatic neuroblastoma renders it largely incurable
with current multimodal treatment. Clinical progression stems mainly from the increasing …

The function of DNA methylation marks in social insects

H Li-Byarlay - Frontiers in Ecology and Evolution, 2016 - frontiersin.org
The social arthropods are characterized by a caste-based division of labor that may be
influenced by epigenetic effects. One of the most important and widely studied epigenetic …

Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait

A Decock, M Ongenaert, B De Wilde, B Brichard… - Epigenetics, 2016 - Taylor & Francis
Stage 4S neuroblastoma (NB) is a special type of NB found in infants with metastases at
diagnosis and is associated with an excellent outcome due to its remarkable capacity to …

Integrated analysis of transcriptome, methylome and copy number aberrations data of marginal zone lymphoma and follicular lymphoma in dog

D Giannuzzi, L Giudice, L Marconato… - Veterinary and …, 2020 - Wiley Online Library
Marginal zone lymphoma (MZL) and follicular lymphoma (FL) are classified as indolent B‐
cell lymphomas in dogs. Aside from the clinical and histopathological similarities with the …

Metastatic state of colorectal cancer can be accurately predicted with methylome

S Albaradei, M Thafar, C Van Neste, M Essack… - Proceedings of the 6th …, 2019 - dl.acm.org
Colorectal cancer (CRC) appears to be the third most common cancer as well as the fourth
most common cause of cancer deaths in the world. Its most lethal states are when it …