Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

Algae synthesise structurally complex glycans to build a protective barrier, the extracellular
matrix. One function of matrix glycans is to slow down microorganisms that try to …

The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

Understanding the mechanisms of antibody-mediated neutralization of SARS-CoV-2 is
critical in combating the COVID-19 pandemic. Based on previous reports of antibody …

Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and
cryptococcal meningitis. The C. neoformans capsular polysaccharide and shed …

Palladium-catalyzed hydrogenolysis is often the final step in challenging natural product
total syntheses and a key step in industrial processes producing fine chemicals. Here, we …

Antibodies play a vital role in the immune response to infectious diseases and can be
administered passively to protect patients. In the case of Cryptococcus neoformans, a WHO …

Carbohydrates dynamically and transiently interact with proteins for cell-cell recognition,
cellular differentiation, immune response, and many other cellular processes. Despite the …

The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical
virulence factor that has historically evaded complete characterization. Cryptococcal …

Humans and other animals produce a diverse collection of antibodies, many of which bind to
carbohydrate chains, referred to as glycans. These anti-glycan antibodies are a critical part …