A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …

Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and
diseases, this topic is very popular and is often taken up by researchers. TMAO is a low …

The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

Background Gut microbial metabolites have been implicated as novel risk factors for
cardiovascular events and premature death. The strength and consistency of associations …

Aims Gut microbiota-derived metabolite trimethylamine-N-oxide (TMAO) is emerging as a
new potentially important cause of increased cardiovascular risk. The purpose of this meta …

Although diet has long been known to contribute to the pathogenesis of cardiovascular
disease (CVD), research over the past decade has revealed an unexpected interplay …

Aims Systemic levels of trimethylamine N-oxide (TMAO), a pro-atherogenic and pro-
thrombotic metabolite produced from gut microbiota metabolism of dietary trimethylamine …