An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
Alopecia Areata (AA) is a common autoimmune disease characterized by non-scarring hair
loss ranging from patches on the scalp to complete hair loss involving the entire body …
loss ranging from patches on the scalp to complete hair loss involving the entire body …
Janus kinase inhibitors for alopecia areata: a systematic review and meta-analysis
Importance Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease.
Several studies have reported outcomes of Janus kinase (JAK) inhibitors for treating AA, but …
Several studies have reported outcomes of Janus kinase (JAK) inhibitors for treating AA, but …
Alopecia areata: current treatments and new directions
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …
JAK-STAT pathway inhibitors in dermatology
The JAK-STAT signaling pathway mediates important cellular processes such as immune
response, carcinogenesis, cell differentiation, division and death. Therefore, drugs that …
response, carcinogenesis, cell differentiation, division and death. Therefore, drugs that …
Clinical and genetic aspects of alopecia areata: a cutting edge review
CY Ho, CY Wu, JYF Chen, CY Wu - Genes, 2023 - mdpi.com
Alopecia areata (AA) is a chronic, non-scarring, immune-mediated skin disease that affects
approximately 0.5–2% of the global population. The etiology of AA is complex and involves …
approximately 0.5–2% of the global population. The etiology of AA is complex and involves …
Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors
AK Gupta, T Wang, S Polla Ravi… - Journal of the …, 2023 - Wiley Online Library
Management options for moderate‐to‐severe alopecia areata (AA) are limited owing to a
lack of safe and effective treatments suitable for long‐term use. However, newer agents …
lack of safe and effective treatments suitable for long‐term use. However, newer agents …
[HTML][HTML] Comparative efficacy and safety of Janus kinase inhibitors used in alopecia areata: a systematic review and meta-analysis
FB Sedeh, TE Michaelsdóttir… - Acta Dermato …, 2023 - ncbi.nlm.nih.gov
The aim of this study was to compare the efficacy and safety of treatment with Janus kinase
inhibitors for alopecia areata, measured by change in Severity of Alopecia Tool (SALT) …
inhibitors for alopecia areata, measured by change in Severity of Alopecia Tool (SALT) …
Janus kinase inhibitors for alopecia areata
BA King, BG Craiglow - Journal of the American Academy of Dermatology, 2023 - Elsevier
Janus kinase (JAK) inhibitors have ushered in a new era in alopecia areata (AA).
Historically, moderate-to-severe AA was refractory to treatment. JAK inhibitors have changed …
Historically, moderate-to-severe AA was refractory to treatment. JAK inhibitors have changed …
Emerging drugs for the treatment of alopecia areata
HA Ramírez-Marín, A Tosti - Expert opinion on emerging drugs, 2022 - Taylor & Francis
ABSTRACT Introduction Alopecia Areata (AA) is the second most common non-scarring hair
loss disorder, with a prevalence of 1 in 1000 and a lifetime incidence of 2% worldwide. Data …
loss disorder, with a prevalence of 1 in 1000 and a lifetime incidence of 2% worldwide. Data …
[HTML][HTML] Recent advances in understanding of the etiopathogenesis, diagnosis, and Management of Hair Loss Diseases
M Kinoshita-Ise, M Fukuyama, M Ohyama - Journal of Clinical Medicine, 2023 - mdpi.com
Hair-loss diseases comprise heterogenous conditions with respective pathophysiology and
clinicopathological characteristics. Major breakthroughs in hair follicle biology and …
clinicopathological characteristics. Major breakthroughs in hair follicle biology and …